Summary
A method is described for increasing the sensitivity of the thiobarbiturate assay
for malondialdehyde by concentrating the coloured reaction product. The basal level
of malondialdehyde-like material in plasma was found to be about 0.03 μM. Platelets
synthesized malondialdehyde when stimulated by collagen or thrombin and also during
the second phase of aggregation induced by ADP or adrenaline.