Thromb Haemost 1959; 03(01): 001-005
DOI: 10.1055/s-0038-1654364
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

Deterioration of AHG (Factor VIII) and Fibrinolysis

P Brakman
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
,
S van Creveld
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
,
E Engelsman
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
,
A van’t Laar
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
,
I. A Mochtar
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
,
H. A Veder*
1   Pediatric Clinic of the University of Amsterdam (The Netherlands); (Head: Prof. Dr. S. van Creveld)
› Author Affiliations
Further Information

Publication History

Publication Date:
08 June 2018 (online)

 

Summary

The possible relationship between antihemophilic globulin (Factor VIII) and fibrinolysis was investigated. No conclusive evidence about the role of fibrinolysis in the deterioration of AHF was obtained but the findings were more against than in favour of the role of fibrinolysis.


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* This work was aided by grants from the Foundation “De Drie Lichten”, in the Netherlands.


  • References

  • 1 Penick G. D, Brinkhous K. M. Relative stability of plasma antihemophilic factor (AHF) under different conditions of storage. Am. J. med. Sci 1956; 232: 434
  • 2 Holburn R. R. Estimation of fibrinolytic activity (fibrin plate method of Astrup and MÜllertz). In Tocantins L. M. "The coagulation of blood" 1955. New York, London: 161
  • 3 Marbet R. "Fibrinolyse". 1956. Hoffmann-La Roche; Basel:
  • 4 Loomis E. C. Estimation of fibrinolysin activity of human plasma or serum in Tocantins, L. M.: "The coagulation of blood". 1955. New York, London: 163
  • 5 Parfentjev I. A, Johnson M. L, Clifton E. E. The determination of plasma fibrinogen by turbidity with ammonium sulfate. Arch. Biochem. Biophys 1953; 46: 470
  • 6 Langdell R. D, Wagner R. H, Brinkhous K. M. Effect of antihemophilic factor on onestage clotting tests. J. Lab. clin. Med 1953; 41: 637
  • 7 Bounameaux Y. Dosage du facteur VIII en un temps. Acta haemat. (Basel) 1957; 17: 355
  • 8 Astrup T. Fibrinolysis in the organism. Blood 1956; 11: 781
  • 9 Brinkhous K. M, Penick G. D, Langdell R. D, Wagner R. H, Graham J. B. Physiologic basis of transfusion therapy in hemophilia. Arch. Path. (Chicago) 1956; 61: 6

  • References

  • 1 Penick G. D, Brinkhous K. M. Relative stability of plasma antihemophilic factor (AHF) under different conditions of storage. Am. J. med. Sci 1956; 232: 434
  • 2 Holburn R. R. Estimation of fibrinolytic activity (fibrin plate method of Astrup and MÜllertz). In Tocantins L. M. "The coagulation of blood" 1955. New York, London: 161
  • 3 Marbet R. "Fibrinolyse". 1956. Hoffmann-La Roche; Basel:
  • 4 Loomis E. C. Estimation of fibrinolysin activity of human plasma or serum in Tocantins, L. M.: "The coagulation of blood". 1955. New York, London: 163
  • 5 Parfentjev I. A, Johnson M. L, Clifton E. E. The determination of plasma fibrinogen by turbidity with ammonium sulfate. Arch. Biochem. Biophys 1953; 46: 470
  • 6 Langdell R. D, Wagner R. H, Brinkhous K. M. Effect of antihemophilic factor on onestage clotting tests. J. Lab. clin. Med 1953; 41: 637
  • 7 Bounameaux Y. Dosage du facteur VIII en un temps. Acta haemat. (Basel) 1957; 17: 355
  • 8 Astrup T. Fibrinolysis in the organism. Blood 1956; 11: 781
  • 9 Brinkhous K. M, Penick G. D, Langdell R. D, Wagner R. H, Graham J. B. Physiologic basis of transfusion therapy in hemophilia. Arch. Path. (Chicago) 1956; 61: 6