Hamostaseologie 1986; 06(05): 193-196
DOI: 10.1055/s-0038-1655159
Originalarbeiten
Schattauer GmbH

Heparansulfate

Ubiquitär vorkommende Komponenten tierischer Zellen mit merkwürdigen Strukturvariabilitäten und verschiedenen pharmakologischen Aktivitäten[*]
C. P. Dietrich
1   Department für Biochemie, Medizinschule Paulista, Sao Paulo, S. P. Brasilien
,
H. B. Nader
1   Department für Biochemie, Medizinschule Paulista, Sao Paulo, S. P. Brasilien
› Author Affiliations
Further Information

Publication History

Publication Date:
25 June 2018 (online)

 

* Die Arbeiten der Autoren wurden unterstützt durch Spenden von FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo), FINEP (Financioadora de Estudos e Projetos), CNPq (Consuelho Nacional de Desenvolvimento Cientifico e Tecnologico)


 
  • Literatur

  • 1 Bianchini P, Osima B, Parma B, Dietrich C P, Takahashi H K, Nader H B. Structural studies and »in vivo« and »in vitro« pharmacological activities of heparin fractions and fragments prepared by chemical and enzymic depolimerization. Thromb Res 1985; 40: 49.
  • 2 Buonassisi V, Root M. Enzymatic degradation of heparin related mucopolysaccharides from the surface of endothelial cell cultures. Biochim Biophys Acta 1975; 385: 1.
  • 3 Cassaro C M F, Dietrich C P. Distribution of sulfated mucopolysaccharides in invertebrates. J Biol Chem 1977; 252: 2254.
  • 4 Cifonelli J A, Dorfman A. Properties of heparin monosulfate (heparitin monosulfate). J Biol Chem 1960; 235: 3283.
  • 5 Colburn P, Buonassisi V. Anti-clotting activity of endothelial cell cultures and heparan sulfate proteoglycans. Biochem Biophys Res Commun 1982; 104: 220.
  • 6 Dietrich C P, de Oca Montes H. Production of heparin-related mucopolysaccharides by mammalian cells in culture. Proc Soc Exp Biol Med 1970; 134: 955.
  • 7 Dietrich C P, Nader H B. Fractionation and properties of heparitin sulfates from beef lung tissue. Biochim Biophys Acta 1974; 343: 34.
  • 8 Dietrich C P, Nader H B, Straus A H. Structural differences of heparan sulfates according to the tissue and species of origin. Biochem Biophys Res Common 1983; 111: 865.
  • 9 Dietrich C P A. model for cell-cell recognition and control of cell growth mediated by sulfated glycosaminoglycans. Brazilian J Med Biol Res 1984; 17: 5.
  • 10 Dunhan J S, Hynes R O. Differences in sulfated macromolecules synthesized by normal and transformed hamster fibroblasts. Biochim Biophys Acta 1978; 506: 242.
  • 11 Gomes P B, Dietrich C P. Distribution of heparin and other sulfated glycosaminoglycans in vertebrates. Comp Biochem Physiol B 1982; 73: 242.
  • 12 Harenberg J, Zimmermann R, Schwarz F, Kubler W. Treatment of heparin-induced thrombocytopenia with thrombosis by new heparinoid. Lancet 1983; I: 986.
  • 13 Henny C P, Cate J W T, Bronswijk H V, Cate H T, Surachno S, Wilmirik J M. Use of a new heparinoid as anticoagulant during acute haemodialysis of patients with bleeding complications. Lancet 1983; I: 890.
  • 14 Jaques L B. Heparins anionic polyelectrolyte drugs. Pharmacol Rev 1980; 31: 99.
  • 15 Jaques L B. Heparin: a unique misunderstood drug. Trends in Pharm Sci 1982; 03: 289.
  • 16 Jorpes J E, Gardell S. On heparin monosulfuric acid. J Biol Chem 1948; 176: 267.
  • 17 Khoory M S, Nesheina M E, Bowie E J W, Mann K G. Circulating heparan sulfate proteoglycan anticoagulant from a patient with a plasma cell disorder. J Clin Invest 1980; 65: 666.
  • 18 Kirk J E. Anticoagulant activity of human arterial mucopolysaccharides. Nature 1959; 184: 369.
  • 19 Koda J E, Bernfield M. Heparan sulfate proteoglycans from mouse mammary epithelial cells. J Biol Chem 1984; 259: 11763.
  • 20 Kraemer P M. Heparan sulfates of cultured cells. I Membrane-asociated cell sub species in Chinese hamster cells. Biochemistry 1971; 10: 1437.
  • 21 Lark M W, Culp L A. Multiple classes of heparan sulfate proteoglycans from fibroblast substratum adhesion sites. J Biol Chem 1984; 259: 6773.
  • 22 Linker A, Hoffman P, Meyer K. Heparitin sulfate. Fed Proc 1958; 17: 264.
  • 23 Linker A, Hovingh P. The use of degradative enzymes as tools for identification and structural analyses of glycosaminoglycans. Fed Proc 1977; 36: 43.
  • 24 Marcum J A, Rosenberg R D. Heparinlike molecules with anticoagulant activity are synthesized by cultured endothelial cells. Biochem Biophys Res Commun 1985; 126: 365.
  • 25 Moritani S, Ohta G. Nature of antithrombin activity of intimai extract from bovine aorta. Jpn Cire J 1973; 37: 619.
  • 26 Nader H B, Dietrich C P. Effect of heparitin sulfate fractions on coagulation and hemostasis. Proc Soc Exp Biol Med 1974; 146: 504.
  • 27 Nader H B, Takahashi H K, Straus A H, Dietrich C P. Selective distribution of the heparin in mammals. Biochim Biophys Acta 1980; 627: 40.
  • 28 Nader H B, Medeiros M G L, Paiva J F, Paiva V M P, Jeronimo S M B, FerreiraTM P C, Dietrich C P. A correlation between the sulfated glycosaminoglycan concentration and degree of salinity of the habitat in fifteen species of the classes crustacea, pelecypoda and gastropoda. Comp Biochem Physiol 1983; 76: 433.
  • 29 Nader H B, Ferreira T M O C, Paiva J F, Medeiros M G L, Jeronimo S M B, Paiva V M P, Dietrich C P. Isolation and structural studies of heparan sulfates and chondroitin sulfates from three species of molluscs. J Biol Chem 1984; 259: 1431.
  • 30 Robinson J, Viti M, Hook M. Structure and properties of an undersulfated heparan sulfate proteoglycan synthesized by a rat hepatoma cell line. J Cell Biol 1984; 98: 946.
  • 31 Saito H, Uzman B G. Production and secretion of chondroitin sulfates and dermatan sulfate by established mammalian cell lines. Biochem Biophys Res Commun 1971; 43: 723.
  • 32 Silva M E, Dietrich C P. Structure of heparin. J Biol Chem 1975; 250: 6841.
  • 33 Silva M E, Dietrich C P, Nader H B. On the structure of the heparitin sulfates. Biochim Biophys Acta 1976; 436: 129.
  • 34 Takahashi H K, Nader H B, Dietrich C P A. method for rapid quantitation and preparation of antithrombin III high affinity heparin fractions. Anal Biochem 1981; 116: 456.
  • 35 Terry A H, Culp L A. Substrate-attached glycoproteins from normal and virus transformed cells. Biochemistry 1974; 12: 414.
  • 36 Toledo O M S, Dietrich C P. Tissue specific distribution of sulfated mucopolysaccharides in mammals. Biochim Biophys Acta 1977; 498: 114.