The Influence of EDTA, Trisodiumcitrate and Heparin on the Ultrastructure of Blood Platelets

J Libánská

doi:10.1055/s-0038-1655595

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1966; 16(03/04): 371-377
DOI: 10.1055/s-0038-1655595

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

The Influence of EDTA, Trisodiumcitrate and Heparin on the Ultrastructure of Blood Platelets

J Libánská

¹Research Institute for Child Development, Pediatric Faculty, Charles University, Prague, and the Laboratory for Electron Microscopy and Experimental Morphology, Czechoslovak Akademy of Sciences

› Author Affiliations

Abstract

Summary

The differences found in the hyalomere of normal human thrombocytes were: the disperse, fine granular arrangement of the hyalomere in the presence of EDTA, fine netlike appearance in the presence of trisodiumcitrate and the fibrillary arrangement of the hyalomere in thrombocytes of heparinised blood.

Differences were also found in the appearance of the granulomere in the presence of heparin, trisodiumcitrate or EDTA. They are evaluated as a result of probable contraction of the granulomere in specimens with heparin.

Because of the ability of thrombocytes from heparinised blood to contract, we explain the present results as a picture of isolated retraction of blood platelets, without degranulation occuring during viscous metamorphosis.

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References

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