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DOI: 10.1055/s-0038-1656173
A Case of Unusual Obstetric Coagulopathy
Publication History
Publication Date:
05 June 2018 (online)
Summary
A case of unusual obstetric coagulopathy is described. A woman near term of a normal pregnancy contracted severe damage to muscles and other tissues. The infant, placenta and uterine function remained unimpaired.
Subsequently to the trauma the patient developed transitoric myoglobinuria and three days later after an otherwise normal delivery a severe hemorrhage occured, which was caused by hypofibrinogenemia. A possible fibrinogenolytic part in this condition is discussed.
A lower nephron nephrosis syndrome developed, which was similar to the syndrome in abruptio placentae. It is considered that the hypofibrinogenemia in this case developed on the basis of a defibrination and dissemination of fibrin in the sense of Schneider.
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Bibliography
- 1 Dieckmann W. Blood Chemistry and renal Function in Abruptio Placentae. Am. J. Obstet. Gynec. 31: 734 1936;
- 2 Jürgens J, und Stein F. Intravasale Gerinnung als koagulopathisches Syndrom nach manueller Lösung der Plazenta. Schweiz, med. Wschr. 12: 346 1954;
- 3 Lewis J. H, und Serguson G. Studies on A Proteolytic Enzyme System of the Blood. II. Fibrinolysokinase Activators for Profibrinolysin. J. clin. Invest. 29: 1059 1950;
- 4 Seegers W. H, und Schneider C. L. Trans. Internat, and Fourth Am. Congress on Obst, and Gynec. Am. J. Obstet. Gynec. 61a: 469 1951;
- 5 Schneider C. L. Obstetric Chock. Acad. Obst. Gyn. 4: 273 1954;
- 6 Spaet T. H, Rosenthal M. C, und Damesher W. Idiopathic Myoglobinuria in Man. Blood 9: 881 1954;
- 7 Tagnon H, und Soulier J. P. The Effect of intravenous Injection of Trypsin Inhibitor on the Coagulation of Blood. Blood 3: 1161 1948;
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Bibliography
- 1 Dieckmann W. Blood Chemistry and renal Function in Abruptio Placentae. Am. J. Obstet. Gynec. 31: 734 1936;
- 2 Jürgens J, und Stein F. Intravasale Gerinnung als koagulopathisches Syndrom nach manueller Lösung der Plazenta. Schweiz, med. Wschr. 12: 346 1954;
- 3 Lewis J. H, und Serguson G. Studies on A Proteolytic Enzyme System of the Blood. II. Fibrinolysokinase Activators for Profibrinolysin. J. clin. Invest. 29: 1059 1950;
- 4 Seegers W. H, und Schneider C. L. Trans. Internat, and Fourth Am. Congress on Obst, and Gynec. Am. J. Obstet. Gynec. 61a: 469 1951;
- 5 Schneider C. L. Obstetric Chock. Acad. Obst. Gyn. 4: 273 1954;
- 6 Spaet T. H, Rosenthal M. C, und Damesher W. Idiopathic Myoglobinuria in Man. Blood 9: 881 1954;
- 7 Tagnon H, und Soulier J. P. The Effect of intravenous Injection of Trypsin Inhibitor on the Coagulation of Blood. Blood 3: 1161 1948;