Ist die intrakoronare Thrombolyse heute noch aktuell?

A. Vogt; K.-L. Neuhaus

doi:10.1055/s-0038-1660315

Hämostaseologie, Table of Contents

Hamostaseologie 1992; 12(02): 047-051
DOI: 10.1055/s-0038-1660315

Übersichtsarbeit/Review Articles

Schattauer GmbH

Ist die intrakoronare Thrombolyse heute noch aktuell?

Authors

A. Vogt

¹Medizinische Klinik II, Städtische Kliniken Kassel (Direktor: Prof. Dr. K.-L. Neuhaus)
K.-L. Neuhaus

¹Medizinische Klinik II, Städtische Kliniken Kassel (Direktor: Prof. Dr. K.-L. Neuhaus)

Abstract

Zusammenfassung

Die intrakoronare Thrombolyse kann thrombotisch verschlossene Infarktgefäße zu einem hohen Prozentsatz rekanalisieren. Dies gelingt mit einer relativ geringen Gesamtdosis von Thrombolytika im Vergleich zur i.v. Gabe. Sie ist aber logistisch sehr aufwendig und kann nur einem Teil der Infarktpatienten zukommen. Zudem entsteht ein Zeitverlust von 40-60 Minuten gegenüber der i. v. Lyse, der durch die intrakoronar raschere Reperfusion nicht wettgemacht wird. Auch nach i. c. Lyse tritt ein globaler Gerinnungsdefekt ein, Blutungskomplikationen sind nicht nachweislich seltener als nach i. v. Kurzlyse. Beim akuten Herzinfarkt ist deshalb heute die i.v. Thrombolyse vorzuziehen.

Schlüsselwörter

Akuter Myokardinfarkt - thrombolyse - streptokinase

Keywords

Acute myocardial infarction - thrombolysis - streptokinase

Full Text

References

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