Side Effects of Phototherapy on Neonates

Fabrízia R. S. Faulhaber; Renato S. Procianoy; Rita C. Silveira

doi:10.1055/s-0038-1667379

American Journal of Perinatology, Inhaltsverzeichnis

Am J Perinatol 2019; 36(03): 252-257
DOI: 10.1055/s-0038-1667379

Review Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Side Effects of Phototherapy on Neonates

Authors

Fabrízia R. S. Faulhaber

¹Postgraduate Program in Child Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Renato S. Procianoy

¹Postgraduate Program in Child Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

²Department of Pediatrics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

³Neonatal Section, Hospital de Clínicas de Porto Alegre, HCPA, Porto Alegre, Brazil
Rita C. Silveira

¹Postgraduate Program in Child Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

²Department of Pediatrics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

³Neonatal Section, Hospital de Clínicas de Porto Alegre, HCPA, Porto Alegre, Brazil

Abstract

Phototherapy in neonates for treatment of pathological jaundice is an effective therapeutic tool that is widely used in neonatal units. Over the past years, a greater concern has emerged about the effects on the immune and inflammatory system and its potential genotoxic and side effects, especially the late ones, possibly associated with childhood diseases, showing that this treatment is not as harmless as previously believed. Numerous studies assessing these possible adverse effects of phototherapy on neonates have been published over the past years. Through this review, we seek to analyze what we know about the side effects of phototherapy in the neonatal period. The main causes of jaundice, phototherapy techniques, acute and late side effects, and effects on the immune and inflammatory system were reviewed. It was concluded that phototherapy is not a treatment free of side effects and further studies need to be conducted to elucidate its harmful effects on neonates.

Keywords

jaundice - hyperbilirubinemia - neonate - phototherapy - side effects

Volltext

Referenzen

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