Open Access
CC BY-NC-ND 4.0 · Laryngorhinootologie 2019; 98(S 02): S41
DOI: 10.1055/s-0039-1685805
Abstracts
Learning based on Case Reports

An unusual cause of otitis media with effusion and clear otorrhea

Authors

  • A Radeloff

    1   Universitäts-HNO-Klinik Oldenburg, Oldenburg
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    Cholesterol granulomas (CGs) are mostly found in the mastoid and temporal apex. A foreign body reaction to degraded blood components is discussed as a underlying pathomechanism. Prostaglandin-D-synthase (a.k.a. beta-trace protein; btp) is found in very high amounts in CSF and is used as a marker for CSF leakage.

    Here we report on two patients with CG and confirmation of btp. The first patient presented with mastoiditis and otitis media with effusion. During mastoidectomy multiple CGs were found. Postoperatively, a btp-positive secretion was present via a tympanostomy tube. Assuming a CSF leakage, two revision surgeries with fluorescein dyed CSF were performed without evidence of a leakage. Granulation and exudate was found in situ.

    The second patient underwent surgery to treat a CG that had destroyed the posterior canal wall. In the collected liquid parts btp was strongly positive (3,3 mg/l).

    The results indicate that btp may be found in CG and potentially in postoperative granulations. This may mimic otoliqhorrhea.


     
    Prof. Dr. med. Andreas Radeloff
    Universitäts-HNO-Klinik Oldenburg,
    Steinweg 13 – 17, 26122
    Oldenburg

    Publication History

    Publication Date:
    12 June 2019 (online)

    © 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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