Semin intervent Radiol 2019; 36(03): 249-254
DOI: 10.1055/s-0039-1694698
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Percutaneous Interventional Management of Spinal Metastasis

Seon-Kyu Lee
1   Department of Radiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York
,
Brandon Weiss
2   Department of Neurosurgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York
,
Vijay Yanamadala
2   Department of Neurosurgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York
,
Allan Brook
1   Department of Radiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York
› Author Affiliations
Further Information

Publication History

Publication Date:
19 August 2019 (online)

Abstract

Spinal metastasis is usually associated with debilitating pain and results in deteriorating life quality. The role of percutaneous management of spinal metastasis has evolved from a diagnostic role to a significant part of therapeutic options in conjunction with conventional management techniques, including radiotherapy and open surgical options. Percutaneous vertebral augmentation (PVA) showed substantial pain reduction, vertebral stabilization, and improvement of quality of life. Minimally invasive local ablative procedures (MILAPs) demonstrated significant pain reduction, local tumor burden control, and improvement of quality of life. Though combined PVA and MILAP's synergistic role in pain reduction may need additional investigation, considering different actions on spine metastasis patients, combining both techniques might beneficial to selected patients. The role of percutaneous management will likely expand since its role in improving patient's quality of life with very minimal procedure-related risk and in conjunction with future technological advancement.

 
  • References

  • 1 Bilsky MH, Lis E, Raizer J, Lee H, Boland P. The diagnosis and treatment of metastatic spinal tumor. Oncologist 1999; 4 (06) 459-469
  • 2 Wong DA, Fornasier VL, MacNab I. Spinal metastases: the obvious, the occult, and the impostors. Spine 1990; 15 (01) 1-4
  • 3 Wibmer C, Leithner A, Hofmann G. , et al. Survival analysis of 254 patients after manifestation of spinal metastases: evaluation of seven preoperative scoring systems. Spine 2011; 36 (23) 1977-1986
  • 4 Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009; 59 (04) 225-249
  • 5 Spratt DE, Beeler WH, de Moraes FY. , et al. An integrated multidisciplinary algorithm for the management of spinal metastases: an International Spine Oncology Consortium report. Lancet Oncol 2017; 18 (12) e720-e730
  • 6 Jakobs TF, Trumm C, Reiser M, Hoffmann RT. Percutaneous vertebroplasty in tumoral osteolysis. Eur Radiol 2007; 17 (08) 2166-2175
  • 7 Fourney DR, Gokaslan ZL. Spinal instability and deformity due to neoplastic conditions. Neurosurg Focus 2003; 14 (01) e8
  • 8 Barr JD, Jensen ME, Hirsch JA. , et al; Society of Interventional Radiology; American Association of Neurological Surgeons; Congress of Neurological Surgeons; American College of Radiology; American Society of Neuroradiology; American Society of Spine Radiology; Canadian Interventional Radiology Association; Society of Neurointerventional Surgery. Position statement on percutaneous vertebral augmentation: a consensus statement developed by the Society of Interventional Radiology (SIR), American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS), American College of Radiology (ACR), American Society of Neuroradiology (ASNR), American Society of Spine Radiology (ASSR), Canadian Interventional Radiology Association (CIRA), and the Society of NeuroInterventional Surgery (SNIS). J Vasc Interv Radiol 2014; 25 (02) 171-181
  • 9 Sciubba DM, Petteys RJ, Dekutoski MB. , et al. Diagnosis and management of metastatic spine disease. A review. J Neurosurg Spine 2010; 13 (01) 94-108
  • 10 Halpin RJ, Bendok BR, Liu JC. Minimally invasive treatments for spinal metastases: vertebroplasty, kyphoplasty, and radiofrequency ablation. J Support Oncol 2004; 2 (04) 339-351 , discussion 352–355
  • 11 Klimo Jr P, Schmidt MH. Surgical management of spinal metastases. Oncologist 2004; 9 (02) 188-196
  • 12 de Ruiter GC, Nogarede CO, Wolfs JF, Arts MP. Quality of life after different surgical procedures for the treatment of spinal metastases: results of a single-center prospective case series. Neurosurg Focus 2017; 42 (01) E17
  • 13 Boriani S, Gasbarrini A, Bandiera S, Ghermandi R, Lador R. En bloc resections in the spine: the experience of 220 patients during 25 years. World Neurosurg 2017; 98: 217-229
  • 14 Klekamp J, Samii H. Surgical results for spinal metastases. Acta Neurochir (Wien) 1998; 140 (09) 957-967
  • 15 Janjan NA. Radiation for bone metastases: conventional techniques and the role of systemic radiopharmaceuticals. Cancer 1997; 80 (8, Suppl): 1628-1645
  • 16 Tong D, Gillick L, Hendrickson FR. The palliation of symptomatic osseous metastases: final results of the Study by the Radiation Therapy Oncology Group. Cancer 1982; 50 (05) 893-899
  • 17 Munk PL, Murphy KJ, Gangi A, Liu DM. Fire and ice: percutaneous ablative therapies and cement injection in management of metastatic disease of the spine. Semin Musculoskelet Radiol 2011; 15 (02) 125-134
  • 18 Callstrom MR, Charboneau JW, Goetz MP. , et al. Painful metastases involving bone: feasibility of percutaneous CT- and US-guided radio-frequency ablation. Radiology 2002; 224 (01) 87-97
  • 19 Yang Z, Yang Y, Zhang Y. , et al. Minimal access versus open spinal surgery in treating painful spine metastasis: a systematic review. World J Surg Oncol 2015; 13: 68
  • 20 Georgy BA. Metastatic spinal lesions: state-of-the-art treatment options and future trends. AJNR Am J Neuroradiol 2008; 29 (09) 1605-1611
  • 21 Berenson J, Pflugmacher R, Jarzem P. , et al; Cancer Patient Fracture Evaluation (CAFE) Investigators. Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial. Lancet Oncol 2011; 12 (03) 225-235
  • 22 Vertebral Augmentation Involving Vertebroplasty or Kyphoplasty for Cancer-Related Vertebral Compression Fractures. A systematic review. Ont Health Technol Assess Ser 2016; 16: 1-202
  • 23 Chew C, Craig L, Edwards R, Moss J, O'Dwyer PJ. Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review. Clin Radiol 2011; 66 (01) 63-72
  • 24 Tian QH, Sun XQ, Lu YY. , et al. Percutaneous vertebroplasty for palliative treatment of painful osteoblastic spinal metastases: a single-center experience. J Vasc Interv Radiol 2016; 27 (09) 1420-1424
  • 25 Chen L, Ni RF, Liu SY. , et al. Percutaneous vertebroplasty as a treatment for painful osteoblastic metastatic spinal lesions. J Vasc Interv Radiol 2011; 22 (04) 525-528
  • 26 Calmels V, Vallée JN, Rose M, Chiras J. Osteoblastic and mixed spinal metastases: evaluation of the analgesic efficacy of percutaneous vertebroplasty. AJNR Am J Neuroradiol 2007; 28 (03) 570-574
  • 27 Tsoumakidou G, Too CW, Koch G. , et al. CIRSE guidelines on percutaneous vertebral augmentation. Cardiovasc Intervent Radiol 2017; 40 (03) 331-342
  • 28 Barragán-Campos HM, Vallée JN, Lo D. , et al. Percutaneous vertebroplasty for spinal metastases: complications. Radiology 2006; 238 (01) 354-362
  • 29 Vogl TJ, Pflugmacher R, Hierholzer J. , et al. Cement directed kyphoplasty reduces cement leakage as compared with vertebroplasty: results of a controlled, randomized trial. Spine 2013; 38 (20) 1730-1736
  • 30 Fourney DR, Schomer DF, Nader R. , et al. Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients. J Neurosurg 2003; 98 (1, Suppl): 21-30
  • 31 Schroeder JE, Ecker E, Skelly AC, Kaplan L. Cement augmentation in spinal tumors: a systematic review comparing vertebroplasty and kyphoplasty. Evid Based Spine Care J 2011; 2 (04) 35-43
  • 32 Korovessis P, Repantis T, Miller LE, Block JE. Initial clinical experience with a novel vertebral augmentation system for treatment of symptomatic vertebral compression fractures: a case series of 26 consecutive patients. BMC Musculoskelet Disord 2011; 12: 206
  • 33 Korovessis P, Vardakastanis K, Vitsas V, Syrimpeis V. Is Kiva implant advantageous to balloon kyphoplasty in treating osteolytic metastasis to the spine? Comparison of 2 percutaneous minimal invasive spine techniques: a prospective randomized controlled short-term study. Spine 2014; 39 (04) E231-E239
  • 34 Lane MD, Le HB, Lee S. , et al. Combination radiofrequency ablation and cementoplasty for palliative treatment of painful neoplastic bone metastasis: experience with 53 treated lesions in 36 patients. Skeletal Radiol 2011; 40 (01) 25-32
  • 35 Wallace AN, Greenwood TJ, Jennings JW. Use of imaging in the management of metastatic spine disease with percutaneous ablation and vertebral augmentation. AJR Am J Roentgenol 2015; 205 (02) 434-441
  • 36 Wallace AN, Robinson CG, Meyer J. , et al. The metastatic spine disease multidisciplinary working group algorithms. Oncologist 2015; 20 (10) 1205-1215
  • 37 Greenwood TJ, Wallace A, Friedman MV, Hillen TJ, Robinson CG, Jennings JW. Combined ablation and radiation therapy of spinal metastases: a novel multimodality treatment approach. Pain Physician 2015; 18 (06) 573-581
  • 38 Wallace AN, Tomasian A, Vaswani D, Vyhmeister R, Chang RO, Jennings JW. Radiographic local control of spinal metastases with percutaneous radiofrequency ablation and vertebral augmentation. AJNR Am J Neuroradiol 2016; 37 (04) 759-765
  • 39 Dupuy DE, Hong R, Oliver B, Goldberg SN. Radiofrequency ablation of spinal tumors: temperature distribution in the spinal canal. AJR Am J Roentgenol 2000; 175 (05) 1263-1266
  • 40 Anchala PR, Irving WD, Hillen TJ. , et al. Treatment of metastatic spinal lesions with a navigational bipolar radiofrequency ablation device: a multicenter retrospective study. Pain Physician 2014; 17 (04) 317-327
  • 41 Goetz MP, Callstrom MR, Charboneau JW. , et al. Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study. J Clin Oncol 2004; 22 (02) 300-306
  • 42 Grönemeyer DH, Schirp S, Gevargez A. Image-guided radiofrequency ablation of spinal tumors: preliminary experience with an expandable array electrode. Cancer J 2002; 8 (01) 33-39
  • 43 Fishman B, Pasternak S, Wallenstein SL, Houde RW, Holland JC, Foley KM. The Memorial Pain Assessment Card. A valid instrument for the evaluation of cancer pain. Cancer 1987; 60 (05) 1151-1158
  • 44 Dupuy DE, Liu D, Hartfeil D. , et al. Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial. Cancer 2010; 116 (04) 989-997
  • 45 Clarençon F, Jean B, Pham HP. , et al. Value of percutaneous radiofrequency ablation with or without percutaneous vertebroplasty for pain relief and functional recovery in painful bone metastases. Skeletal Radiol 2013; 42 (01) 25-36
  • 46 Halpin RJ, Bendok BR, Sato KT, Liu JC, Patel JD, Rosen ST. Combination treatment of vertebral metastases using image-guided percutaneous radiofrequency ablation and vertebroplasty: a case report. Surg Neurol 2005; 63 (05) 469-474 , discussion 474–475
  • 47 Tomasian A, Wallace A, Northrup B, Hillen TJ, Jennings JW. Spine cryoablation: pain palliation and local tumor control for vertebral metastases. AJNR Am J Neuroradiol 2016; 37 (01) 189-195
  • 48 Masala S, Roselli M, Manenti G, Mammucari M, Bartolucci DA, Simonetti G. Percutaneous cryoablation and vertebroplasty: a case report. Cardiovasc Intervent Radiol 2008; 31 (03) 669-672
  • 49 Kurup AN, Callstrom MR. Ablation of skeletal metastases: current status. J Vasc Interv Radiol 2010; 21 (8, Suppl): S242-S250
  • 50 Kastler A, Alnassan H, Aubry S, Kastler B. Microwave thermal ablation of spinal metastatic bone tumors. J Vasc Interv Radiol 2014; 25 (09) 1470-1475
  • 51 Kam NM, Maingard J, Kok HK. , et al. Combined vertebral augmentation and radiofrequency ablation in the management of spinal metastases: an update. Curr Treat Options Oncol 2017; 18 (12) 74
  • 52 Reyes M, Georgy M, Brook L. , et al. Multicenter clinical and imaging evaluation of targeted radiofrequency ablation (t-RFA) and cement augmentation of neoplastic vertebral lesions. J Neurointerv Surg 2018; 10 (02) 176-182
  • 53 Hoffmann RT, Jakobs TF, Trumm C, Weber C, Helmberger TK, Reiser MF. Radiofrequency ablation in combination with osteoplasty in the treatment of painful metastatic bone disease. J Vasc Interv Radiol 2008; 19 (03) 419-425
  • 54 Orgera G, Krokidis M, Matteoli M. , et al. Percutaneous vertebroplasty for pain management in patients with multiple myeloma: is radiofrequency ablation necessary?. Cardiovasc Intervent Radiol 2014; 37 (01) 203-210