Zeitschrift für Phytotherapie 2019; 40(S 01): S35-S36
DOI: 10.1055/s-0039-1697315
Poster
Georg Thieme Verlag KG Stuttgart · New York

Data on Althaea officinalis L. root extract from the PhytoVIS study

J Möller
1   Bayer Consumer Health, Innovation & Development, Phytomedicines Supply and Development Center, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany
,
E Raskopf
2   ClinNovis GmbH, Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
O Greinert
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
G Zadoyan
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
S Schleicher
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
K Shah-Hosseini
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
T Wegener
4   Kooperation Phytopharmaka GbR, Bonn, Germany
5   Consulting HMP, Weinheim, Germany
,
O Kelber
1   Bayer Consumer Health, Innovation & Development, Phytomedicines Supply and Development Center, Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany
4   Kooperation Phytopharmaka GbR, Bonn, Germany
,
J Singh
2   ClinNovis GmbH, Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
,
K Kraft
4   Kooperation Phytopharmaka GbR, Bonn, Germany
6   Lehrstuhl für Naturheilkunde, Universitätsmedizin Rostock, Rostock, Germany
,
K Nieber
4   Kooperation Phytopharmaka GbR, Bonn, Germany
7   Institute of Pharmacy University of Leipzig, Leipzig, Germany
,
R Mösges
2   ClinNovis GmbH, Cologne, Germany
3   Institute for Medical Statistics and Computational Biology, University Hospital Cologne, Cologne, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
09 September 2019 (online)

 
 

    Introduction:

    STW 42, a marshmallow (Althaea officinalis L.) based cough medicine, is used in the therapy of mucosal irritation with dry cough, a condition frequently occurring in the cold season. It acts locally, in contrast to a number of other therapeutic options with systemic effects and, accordingly, a higher potential of side effects. The PhytoVIS study is a pharmaco-epidemiological data base on the use of herbal medicinal products [1], containing data from 20,870 users of herbal medicinal products, which have been collected in doctors' practices and pharmacies in compliance to the ENCePP Code of Conduct [2]. It was accessed as a potential source of information on patients using a herbal medicine and their subjective rating of the efficacy and tolerability of the products used.

    Methods:

    The database was screened for users of STW 42 and information on indications, treatments, co-medication and tolerability was evaluated.

    Results:

    Interviewed patients included all age groups and most patients described their symptoms as cough resp. dry cough. 126 patients used STW 42 syrup and 15 STW 42 lozenges. Nearly 90% of the users rated the efficacy of the product as moderate to very good, only 3.5% reported their condition to be unchanged or worsened. The effect tended to be rated better in moderately severe as compared to mild symptoms. Overall tolerability was very good.

    Conclusion:

    Together with the information on more than a thousand patients documented in earlier surveys [3, 4], these data underline the efficacy of STW 42 in relieving cough symptoms and its good tolerability. They further support the use of said medicine not only in adults, but also in pediatric patients, where it presents itself to be a safe and highly used option. Given the comparatively small size of the patient group, the data from the PhytoVIS study proved to give a useful insight into epidemiology as well as data regarding efficacy and safety of Phytohustil®.

    Acknowledgment:

    The study was supported by Kooperation Phytopharmaka GbR, Bonn, Germany.

    References:

    [1] Raskopf E et al. Z Phytother 2017; 38 (Suppl. 1): S40-S41

    [2] European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), 2018. EMA/929209/2011

    [3] Fasse M et al. Paed 2005; 11: 3 – 8

    [4] Fink C et al. Z Phytother 2017; 38 (Suppl. 1): S22


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