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J Neurol Surg B Skull Base 2021; 82(05): 522-527
DOI: 10.1055/s-0040-1712179
Original Article

Surgical Experience in Prevention of Postoperative CSF Leaks Using Abdominal Fat Grafts in Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas

Stephen Ahn
1   Department of Neurosurgery, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Republic of Korea
,
Jae-Sung Park
1   Department of Neurosurgery, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Republic of Korea
,
Do H. Kim
2   Department of Otolaryngology–Head and Neck Surgery, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Republic of Korea
,
Sung W. Kim
2   Department of Otolaryngology–Head and Neck Surgery, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Republic of Korea
,
Sin-Soo Jeun
1   Department of Neurosurgery, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Republic of Korea
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Abstract

Objective Cerebrospinal fluid (CSF) leaks are the most common complication during endonasal endoscopic transsphenoidal approach (EETSA) and prevention of postoperative CSF leaks is critical. In this study, we report a single surgeon's experience of sellar floor reconstruction using abdominal fat grafts for prevention of postoperative CSF leaks in EETSA for pituitary adenomas.

Study Design This study is presented as case series with retrospective chart review.

Setting Present study was conducted at tertiary referral center.

Participants A total of 216 patients who underwent surgery via EETSA for pituitary adenomas between 2008 and 2018 at our institution were evaluated. When an intraoperative CSF leak occurred, sellar floor reconstruction was performed using a fat graft harvested from the abdomen via a 2-cm skin incision.

Main Outcome Measures Primary outcome and measures of this study was postoperative CSF leaks.

Results A total of 53 patients showed intraoperative CSF leaks (24.5%) and 2 patients showed postoperative CSF leaks (0.93%). There were no postoperative CSF leaks in any patients who showed intraoperative CSF leaks and received sellar floor reconstruction using fat grafts. There were also no postoperative CSF leaks in 12 patients who received preventative sellar floor reconstruction using fat grafts due to extensive arachnoid herniation without intraoperative CSF leaks. However, there were two postoperative CSF leaks in patients who did not show intraoperative CSF leaks and did not receive sellar floor reconstruction.

Conclusion The effectiveness of sellar floor reconstruction using abdominal fat grafts in patients receiving EETSA for pituitary adenoma was reported. We suggest that identification of intraoperative CSF leaks is important and preventive sellar floor reconstruction without evidence of intraoperative CSF leaks can also be beneficial.

Keywords

CSF leak - pituitary adenoma - fat graft - endoscopic - endonasal - transsphenoidal


Publication History

Received: 19 April 2019

Accepted: 19 March 2020

Article published online:
20 August 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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