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Int J Angiol 2020; 29(04): 237-244
DOI: 10.1055/s-0040-1714751
Original Article

Inflammatory Conditions in Acute Coronary Syndrome Patients Treated with Percutaneous Coronary Intervention of Saphenous Vein Graft

Tayyar Cankurt
1   Cardiology Clinic, Amasya University Sabuncuoglu Sereefeddin State Hospital, Ankara, Turkey
,
İbrahim E. Celik
2   Department of Cardiology, University of Health Sciences, Ankara Education and Research Hospital, Ankara, Turkey
,
Selcuk Ozturk
2   Department of Cardiology, University of Health Sciences, Ankara Education and Research Hospital, Ankara, Turkey
,
Orhan Maden
3   Department of Cardiology, University of Health Sciences, Ankara Bilkent City Hospital, Ankara, Turkey
› Author Affiliations Funding The authors received no financial support for the research, authorship, and/or publication of this article.
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Abstract

The study aimed to evaluate the inflammatory blood parameters in acute coronary syndrome (ACS) patients with a history of coronary artery bypass graft (CABG) and treated with percutaneous coronary intervention (PCI) of saphenous vein graft (SVG). A total of 347 patients who underwent urgent SVG PCI with the diagnosis of ACS were included in the study. After the application of exclusion criteria, 79 patients were allocated into two groups, namely, successful PCI (n = 59) and unsuccessful PCI (n = 20), and included in the statistical analysis. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) levels were significantly higher in patients with unsuccessful SVG PCI. In the logistic regression analysis, PLR, C-reactive protein, and diabetes mellitus emerged as independent factors associated with unsuccessful SVG PCI. The area under the curve for PLR was 0.70 (95% confidence interval: 0.55–0.85, p = 0.006). The cut-off value of PLR (128.99) was associated with 70.0% sensitivity and 69.5% specificity. Elevated inflammatory status is associated with unsuccessful PCI of SVG in ACS patients. Increased PLR levels on admission is an independent predictor of this situation. This cheap and simple marker can help us to predict unsuccessful SVG PCI in ACS patients.

Keywords

saphenous vein graft - platelet-to-lymphocyte ratio - neutrophil-to-lymphocyte ratio - inflammation - percutaneous coronary intervention

Authors' Note

All authors have substantial contributions to conception and design or acquisition of data, analysis, and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version to be published.


Disclosure

The results of this study were presented at 35th Turkish Cardiology Congress with International Participation as a poster presentation.




Publication History

Article published online:
30 August 2020

© 2020. International College of Angiology. This article is published by Thieme.

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