CC BY-NC-ND 4.0 · Laryngorhinootologie 2021; 100(S 02): S26
DOI: 10.1055/s-0041-1727662
Abstracts
Imaging / Sonography: Salivary Glands / Facialis

The Role of Multimodal Ultrasound in the Characterization of Parotid Gland Lesions

Katharina Margherita Wakonig
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte, 10117 Berlin
,
P Arens
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte, 10117 Berlin
,
Markus Herbert Lerchbaumer
2   Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Campus Charité Mitte, 10117 Berlin
,
L Zhang
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte, 10117 Berlin
,
T Fischer
2   Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Campus Charité Mitte, 10117 Berlin
,
H Olze
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte, 10117 Berlin
,
S Dommerich
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte, 10117 Berlin
› Author Affiliations
› Further Information
Also available at
 
 

    Introduction Ultrasound (US) is a highly sensitive and specific tool in the diagnostic of parotid gland lesions (PGL). Even though most of the PGL are benign there is a risk of malignant degeneration. In the current practice, radiological imaging is not always capable of differentiating between malign and benign. Operative resection is still the gold standard approach. This study aims to ameliorate the differentiation of different subgroups by using multimodal US.

    Material and Methods B-mode US, color duplex imaging, shear-wave elastography (SWE) and contrast enhanced ultrasound (CEUS) were applied for all patients before surgery. Raw data (90 seconds video loop) were quantified by using the postprocessing software VueBox ® (Braco). CEUS time-intensity-curves of histologically defined tumor entities were analyzed.

    Results In this preliminary data analysis 32 patients 7 were diagnosed with malign and 25 with benign (14 Warthin's tumors (WT), 7 pleomorphic adenomas (PA), 3 cysts, 1 scar) PGL. Intensity parameters (meanLin, peak enhancement, wash-in/out-rate and perfusion characteristics) showed a significant difference between WT and PA (all p <  0.05). The median transit time was the only time parameter allowing a significant differentiation between groups (p=0.02). No significant perfusion parameter and SWE differences between malign and benign PGL were retrieved (all p >0.05).

    Discussion In this preliminary data analysis we can already show significant differences in contrast enhancing patterns of the most common benign PGL (WT, PA). While differences between entities could be demonstrated, no significant differences regarding differentiation of malignancy was observed.

    Poster-PDF A-1589.pdf


    #

    Conflict of interest

    Der Erstautor gibt keinen Interessenskonflikt an.

    Address for correspondence

    Wakonig Katharina Margherita
    Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte
    10117 Berlin

    Publication History

    Article published online:
    13 May 2021

    © 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

    Georg Thieme Verlag KG
    Rüdigerstraße 14, 70469 Stuttgart, Germany