Dtsch Med Wochenschr 2017; 142(07): 506-510
DOI: 10.1055/s-0042-122474
Klinischer Fortschritt
Kardiologie
© Georg Thieme Verlag KG Stuttgart · New York

Update Vorhofohrverschluss 2017

Update on Left Atrial Appendage Closure 2017
Volker Schulze
1   Klinik für Kardiologie, Pneumologie und Angiologie, Herzzentrum der Heinrich-Heine-Universität, Düsseldorf
,
Tobias Zeus
1   Klinik für Kardiologie, Pneumologie und Angiologie, Herzzentrum der Heinrich-Heine-Universität, Düsseldorf
,
Horst Sievert
2   Cardio Vasculäres Centrum CVC, Frankfurt
› Author Affiliations
Further Information

Publication History

Publication Date:
07 April 2017 (online)

Was ist neu?

Indikation zum Vorhofohrverschluss Bei Kontraindikation zur oralen Antikoagulation kann leitliniengemäß ein interventioneller Vorhofohrverschluss erwogen werden. Es stehen mittlerweile anerkannte Algorithmen zur Patientenselektion zur Verfügung. Die Erfolgsrate und die Sicherheit des Eingriffes haben sich in den letzten Jahren deutlich verbessert.

Methoden zum Vorhofohrverschluss Zum perkutanen Vorhofohrverschluss stehen verschiedene Devices zur Verfügung. Die besten klinischen Daten existieren für den Watchman und den ACP/Amulet-Okkluder. Hier konnten mittlerweile zahlreiche Studien einen guten Langzeiterfolg der Therapie belegen. Bei zuletzt deutlich verbessertem Sicherheitsprofil kann die Prozedur mit hoher Erfolgsrate durchgeführt werden.

 
  • Literatur

  • 1 Kirchhof P. Benussi S. Kotecha D. et al. ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO). Eur Heart J 2016; DOI: 10.1093/eurheartj/ehw210.
  • 2 Heeringa J. van der Kuip DA. Hofman A. et al. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J 2006; 27: 949-953
  • 3 Lloyd-Jones DM. Wang TJ. Leip EP. et al. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation 2004; 110: 1042-1046
  • 4 Go AS. Hylek EM. Phillips KA. et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. Jama 2001; 285: 2370-2375
  • 5 Hart RG. Halperin JL. Atrial fibrillation and thromboembolism: a decade of progress in stroke prevention. Ann Intern Med 1999; 131: 688-695
  • 6 Blackshear JL. Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg 1996; 61: 755-759
  • 7 Lip GY. Nieuwlaat R. Pisters R. et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest 2010; 137: 263-272
  • 8 Roldan V. Marin F. Manzano-Fernandez S. et al. The HAS-BLED score has better prediction accuracy for major bleeding than CHADS2 or CHA2DS2-VASc scores in anticoagulated patients with atrial fibrillation. J Am Coll Cardiol 2013; 62: 2199-2204
  • 9 [Anonym]. Transesophageal echocardiographic correlates of thromboembolism in high-risk patients with nonvalvular atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Ann Intern Med 1998; 128: 639-647
  • 10 Aberg H. Atrial fibrillation­­. I. A study of atrial thrombosis and systemic embolism in a necropsy material. Acta Med Scand 1969; 185: 373-379
  • 11 Manning WJ. Silverman DI. Waksmonski CA. et al. Prevalence of residual left atrial thrombi among patients with acute thromboembolism and newly recognized atrial fibrillation. Arch Intern Med 1995; 155: 2193-2198
  • 12 Boersma LV. Schmidt B. Betts TR. et al. Implant success and safety of left atrial appendage closure with the WATCHMAN device: peri-procedural outcomes from the EWOLUTION registry. Eur Heart J 2016; 37: 2465-2474
  • 13 Holmes Jr. DR. Kar S. Price MJ. et al. Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J Am Coll Cardiol 2014; 64: 1-12
  • 14 Holmes Jr DR. Doshi SK. Kar S. et al. Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation: A Patient-Level Meta-Analysis. J Am Coll Cardiol 2015; 65: 2614-2623
  • 15 Reddy VY. Mobius-Winkler S. Miller MA. et al. Left atrial appendage closure with the Watchman device in patients with a contraindication for oral anticoagulation: the ASAP study (ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology). J Am Coll Cardiol 2013; 61: 2551-2556
  • 16 O'Brien EC. Holmes DN. Ansell JE. et al. Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. Am Heart J 2014; 167: 601-609 e601
  • 17 Steinberg BA. Greiner MA. Hammill BG. et al. Contraindications to anticoagulation therapy and eligibility for novel anticoagulants in older patients with atrial fibrillation. Cardiovas Ther 2015; 33: 177-183
  • 18 Kirchhof P. Benussi S. Kotecha D. et al. ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO). Europace 2016; DOI: 10.1093/europace/euw295.
  • 19 Reddy VY. Doshi SK. Sievert H. et al. Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial. Circulation 2013; 127: 720-729
  • 20 Ruff CT. Giugliano RP. Braunwald E. et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet 2014; 383: 955-962
  • 21 Shah M. Avgil TM. Jackevicius CA. et al. Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis. Circulation 2014; 129: 1196-1203
  • 22 Piccini JP. Stevens SR. Chang Y. et al. Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts. Circulation 2013; 127: 224-232
  • 23 Piccini JP. Sievert H. Patel MR. Left atrial appendage occlusion: rationale, evidence, devices, and patient selection. European heart journal 2016; DOI: 10.1093/eurheartj/ehw330.
  • 24 Gillinov M. Moskowitz AJ. Argenziano M. Surgical Ablation for Atrial Fibrillation. N Engl J Med 2015; 373: 484
  • 25 Aryana A. Singh SK. Singh SM. et al. Association between incomplete surgical ligation of left atrial appendage and stroke and systemic embolization. Heart rhythm 2015; 12: 1431-1437
  • 26 Whitlock R. Healey J. Vincent J. et al. Rationale and design of the Left Atrial Appendage Occlusion Study (LAAOS) III. Annals of cardiothoracic surgery 2014; 3: 45-54
  • 27 Holmes DR. Reddy VY. Turi ZG. et al. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet 2009; 374: 534-542
  • 28 Tzikas A. Shakir S. Gafoor S. et al. Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicentre experience with the AMPLATZER Cardiac Plug. EuroIntervention 2016; 11: 1170-1179
  • 29 Freixa X. Abualsaud A. Chan J. et al. Left atrial appendage occlusion: initial experience with the Amplatzer Amulet. Int J Cardiol 2014; 174: 492-496
  • 30 Abualsaud A. Freixa X. Tzikas A. et al. Side-by-Side Comparison of LAA Occlusion Performance With the Amplatzer Cardiac Plug and Amplatzer Amulet. J Invasive Cardiol 2016; 28: 34-38
  • 31 Price MJ. Gibson DN. Yakubov SJ. et al. Early safety and efficacy of percutaneous left atrial appendage suture ligation: results from the U.S. transcatheter LAA ligation consortium. J Am Coll Cardiol 2014; 64: 565-572
  • 32 Chatterjee S. Herrmann HC. Wilensky RL. et al. Safety and Procedural Success of Left Atrial Appendage Exclusion With the Lariat Device: A Systematic Review of Published Reports and Analytic Review of the FDA MAUDE Database. JAMA Intern Med 2015; 175: 1104-1109
  • 33 Lakkireddy D. Afzal MR. Lee RJ. et al. Short and long-term outcomes of percutaneous left atrial appendage suture ligation: Results from a US multicenter evaluation. Heart rhythm 2016; 13: 1030-1036
  • 34 Bartus K. Gafoor S. Tschopp D. et al. Left atrial appendage ligation with the next generation LARIAT(+) suture delivery device: Early clinical experience. Int J Cardiol 2016; 215: 244-247
  • 35 Gunda S. Reddy M. Pillarisetti J. et al. Differences in complication rates between large bore needle and a long micropuncture needle during epicardial access: time to change clinical practice?. Circ Arrhythm Electrophysiol 2015; 8: 890-895