Abstract
This Account summarizes the highly appealing dearomatization reactions of β-naphthols
for the synthesis of highly functionalized, three-dimensional structures starting
with simple planar aromatic compounds. The reactions are categorized mainly from the
viewpoint of the construction of carbon–hydrogen, carbon–carbon, and carbon–hetero
bonds (C–N/O, C–Cl, C–F) at the α-position of β-naphthols. The dearomatized products
play an important role in organic synthesis and materials science.
1 Introduction
2 Construction of Carbon–Hydrogen Bonds at the α-Position of β-Naphthols
3 Construction of Carbon–Carbon Bonds at the α-Position of β-Naphthols
4 Construction of Carbon–Nitrogen/Oxygen Double Bond at the α-Position of β-Naphthols
5 Construction of Carbon–Carbon and Carbon–Oxygen Bonds at the α-Position of β-Naphthols
6 Construction of Carbon–Halogen Bonds at the α-Position of β-Naphthols
7 Conclusion
Key words
β-naphthol - dearomatization - naphthalen-2-one
