Abstract
In recent years great emphasis has been placed on the role of central aortic blood
pressure as measured non invasively using pulse wave analysis in pathophysiology of
cardiovascular diseases and clinical aspects of hypertension. The difference of blood
pressure between the central aorta and the brachial artery (amplification) is not
constant but varies according to physiological, pathological and pharmacological mechanisms.
Central aortic blood pressure is more strongly related to cardiovascular organ damages
than does brachial pressure. Several antihypertensive drugs have different effects
on aortic blood pressure as compared with brachial pressure. Central aortic blood
pressure emerges superior to brachial pressure as target blood pressure in antihypertensive
treatment.
Die Messung des Blutdruckes ist wichtiger Bestandteil vieler Untersuchungen. Dabei
gewinnt der zentrale aortale Blutdruck zunehmend an Interesse. Welche Verbindungen
dieser Parameter zu hypertensiven Organschäden und verschiedenen Hypertonieformen
hat und welche Rolle er bei der antihypertensiven Therapie spielt, wird in diesem
Beitrag aufgezeigt.
Schlüsselwörter
Zentraler aortaler Blutdruck - Diagnostik - Hypertonie - Augmentation - antihypertensive
Therapie
Key words
central aortic pressure - diagnosis - hypertension - augmentation - antihypertensive
therapy
