Pharmacopsychiatry 2017; 50(05): 169-171
DOI: 10.1055/s-0043-118483
Editorial
© Georg Thieme Verlag KG Stuttgart · New York

Editorial to Driving Ability and Psychotropic Drugs

Gerd Laux
1   Institute of Psychological Medicine, Soyen, Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany
,
Michael Bauer
2   Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital Dresden, Dresden, Germany
› Author Affiliations
Further Information

Publication History

received16 August 2017
revised16 August 2017

accepted 16 August 2017

Publication Date:
12 September 2017 (online)

Pharmacoepidemiological data show the highly frequent use of psychotropic drugs. According to the „Arzneiverordnungs-Report“ psychotropic drugs range second among the most prescribed medicines in Germany with antidepressants being the dominating class by far [1]. Modern societies demand a high grade of mobility, driving a car is vital for the functional autonomy of patients to take part in activities of daily living and are frequently obligatory for many professions. Psychiatric illness and psychopharmacological treatments may impair driving ability [2] [3] [4] [5] [6]forreview]. Therefore, road safety under psychotropic treatment is of high societal relevance, and the reason for highlighting this rarely covered field of psychopharmacology in this special issue of Pharmacopsychiatry.

 
  • References

  • 1 Schwabe U, Paffrath D. Arzneiverordnungs-Report. Heidelberg: Springer; 2016
  • 2 Brunnauer A, Laux G. Fahrtüchtigkeit und psychische Erkrankung. In: Möller HJ, Laux G, Kapfhammer HP. Hrsg Psychiatrie, Psychosomatik, Psychotherapie. Band 4. 5.Auflage Heidelberg, Berlin: Springer; 2017
  • 3 Brunnauer A, Laux G. Psychopharmaka und Fahrtüchtigkeit. In: Riederer PF, Laux G. Hrsg Grundlagen der Neuro-Psychopharmakologie. Ein Therapiehandbuch. Wien New York: Springer; 2010. p 475-482
  • 4 DRUID Driving under the influence of Drugs, Alcohol and Medicines. 6th Framework Programme. Deliverable 1.1.2b, 4.1.1 http://www.druid-project.eu/Druid/EN/deliverales-list/downloads/Deliverable_1 1 2, 4 1 1.html?nn = 613800 [Accessed 1.8.2017]
  • 5 Dassanayake T, Michie P, Carter G. et al. Effects of benzodiazepines, antidepressants and opioids on driving: A systemic review and meta-analysis of epidemiological and experimental evidence. Drug Saf 2011; 34: 125-156
  • 6 De las Cuevas C, Ramallo Y, Sanz EJ. Psychomotor performance and fitness to drive: The influence of psychiatric disease and its pharmacological treatment. Psychiatry Res 2010; 176: 236-241
  • 7 Brunnauer A, Widder B, Laux G. Grundlagen der Fahreignungsbeurteilung bei neurologischen und psychischen Erkrankungen. Nervenarzt 2014; 85: 805-810
  • 8 Brunnauer A, Laux G. The effects of most commonly prescribed second generation antidepressants on driving ability: A systematic review. J Neural Transm 2013; 120: 225-232
  • 9 Fahrerlaubnisverordnung- FeV (Fassung vom 16.12.2014). http://www.fahrerlaubnisrecht.de/FeV/FeV_Inhaltsverzeichnis.htm [Accessed: 10.07.2017]
  • 10 Gräcmann N, Albrecht M. Begutachtungsleitlinien zur Kraftfahreignung. Bundesanstalt für Straßenwesen. Berichte der Bundesanstalt für Straßenwesen. Mensch und Sicherheit. Heft M115. Bergisch Gladbach 2014
  • 11 Laux G, Brunnauer A. Fahrtauglichkeit bei affektiven Störungen und unter Psychopharmaka. Nervenarzt 2014; 85: 822-828
  • 12 Brunnauer A, Buschert V, Fric M. et al. Driving performance and psychomotor function in depressed patients treated with agomelatine or venlafaxine. Pharmacopsychiatry 2015; 48: 65-71
  • 13 Smink BE, Egberts AC, Lusthof KJ. et al. The relationship between benzodiazepine use and traffic accidents: A systematic literature review. CNS Drugs 2010; 24: 639-653
  • 14 Laar Mv, Volkerts E. Driving and benzodiazepine use. CNS Drugs 1998; 10: 383-396
  • 15 Kawano N, Iwamoto K, Iidaka T. et al. Effects of mild cognitive impairment on driving performance in older drivers. J Am Geriatr Soc 2012; 60: 1379-1381
  • 16 Haussmann R, Wagner T, Müller D. et al. Beurteilung der Fahrtauglichkeit bei Patienten mit MCI und demenziellen Syndromen. Nervenarzt 2017; 88: 247-253
  • 17 Dubinsky R, Stein A, Lyons K. Practice parameters: Risk of driving and Alzheimer‘s disease (an evidence-based review). Report of the quality standards subcommittee of the American Academy of Neurology. Neurology 2000; 54: 2205-2211
  • 18 Brunnauer A, Buschert C, Laux G. Demenz und Autofahren. Nervenarzt 2014; 85: 811-815
  • 19 Turk K, Dugan E. Research brief: A literature review of frontotemporal dementia and driving. Am J Alzheimers Dis Other Demen 2014; 29: 404-408
  • 20 Brunnauer A, Laux G, Zwick S. Driving simulator performance and psychomotor functions of patients treated with antipsychotics. Eur Arch Psychiatry Clin Neurosci 2009; 259: 483-489
  • 21 Brunnauer A, Laux G, Geiger E. et al. The impact of antipsychotics on psychomotor performance with regard to car driving skills. J Clin Psychopharmacol 2004; 24: 155-160
  • 22 Kagerer S, Winter C, Möller HJ. et al. Effects of haloperidol and atypical neuroleptics on psychomotor performance and driving ability in schizophrenic patients. Results from an experimental study. Neuropsychobiology 2003; 47: 212-218
  • 23 Soyka M, Winter C, Kagerer S. et al. Effects of haloperidol and risperidone on psychomotor performance relevant to driving ability in schizophrenic patients compared to healthy controls. J. Psychiatry Res 2005; 33: 101-108
  • 24 Cox DJ, Davis M, Mikami AY. et al. Long-acting methylphenidate reduces collison rates of young adult drivers with attention-deficit/hyperactivity disorder. J Clin Psychopharmacol 2012; 32: 225-230