Abstract
Patients with neurodegenerative movement disorders can develop cognitive impairment
during the disease. Cognitive symptoms have been associated with decreased quality
of life, higher caregiver burden, and earlier institutionalization, and are therefore
critical for physicians to understand and address. The evaluation of cognitive performance
of patients with neurodegenerative movement disorders is important for providing adequate
diagnosis, management, prognosis, and support patients and their caregivers. In this
review, we discuss the features of the cognitive impairment profile of commonly encountered
movement disorders: Parkinson's disease, dementia with Lewy bodies, multiple system
atrophy, progressive supranuclear palsy, corticobasal syndrome, and Huntington's disease.
In addition, we provide neurologists with practical guidance and evaluation tools
for the assessment and management of these challenging patients.
Keywords
neurodegenerative movement disorders - cognitive impairment - neuropsychiatric symptoms
- dementia