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Semin Musculoskelet Radiol 2024; 28(05): 515-527
DOI: 10.1055/s-0044-1788692
DOI: 10.1055/s-0044-1788692
Review Article
Bone Marrow and Metabolic Bone Disease
Abstract
The bone marrow represents one of the largest organs in the body, with a relevant metabolic role that continues to be investigated. Numerous studies have focused on marrow adipose tissue (MAT). Evidence indicates that the bone marrow adipocytes do not only work as storage tissue but also consist of endocrine and paracrine cells, with the potential to contribute to local and systemic metabolism. MAT plays a role in bone health through its interaction with the other components of bone. Many metabolic disorders (osteoporosis, obesity, diabetes) have a complex and still not well-established or understood relationship with bone health. This article surveys the literature on the relationship of bone marrow and metabolic disorders, and how it is being studied using imaging techniques, with a special focus on bone health.
Keywords
bone marrow imaging - osteoporosis - vertebral fracture - oncologic imaging - marrow adipose tissuePublikationsverlauf
Artikel online veröffentlicht:
15. Oktober 2024
© 2024. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
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