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DOI: 10.1055/s-0044-1797939
HISTORICAL ANALYSIS OF 2003 TO 2013 OF THE CLINIC EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH IN SITU DE BREAST CARCINOMA IN MANAUS - AM
Introduction: Breast cancer is pointed as one of the main causes of death among women. In its classification, carcinoma in situ is characterized by an abnormal multiplication of the ductolobular breast cells. The high morbidity and mortality rates and the occurrence of this disease worldwide show the importance of developing and investigating means for early detection and diagnosis. Objective: To draw a social epidemiological and clinical profile of patients diagnosed with breast cancer in situ and treated at a referral center for oncology in the Amazon. Method: Retrospective longitudinal descriptive study was performed based on the analysis of 75 medical records of patients diagnosed with carcinoma in situ between 2003 and 2013. During collection, data regarding gender, age, origin, histological type and treatment were cataloged. Inclusion criteria were patients with in situ breast carcinoma. The exclusion criterion was medical records that were not properly completed. Results: The survey was conducted in only 56 records, considering that 19 of them had incomplete information. Regarding gender, only one patient was male, the others were female. The age range ranged from 30 to 63 years. Of the total patients, the predominant age group is 50-59 years old with 36%, followed by the age group 40-49 years old with 30%, the age group older than 60 years 21% and the lowest incidence is between 30-59 years old. 39 presented 13%. Regarding the naturalness, the prevalence of patients in Manaus is 75%, while 16% are from the interior of the state, and 0.9% from other states in the northern region (Pará, Maranhão and Acre). Regarding the histological type of the tumor, there was a predominance of the unspecified DCIS type with 55%, followed by the Comedo type with 27%, the Solid type presented the incidence with 9%, the Cribiform with 7% and the Papillary and Micro papillary type, both having the same incidence of 2% each. Conclusion: It showed an incidence of 3.5% of patients with DCIS, being the most affected age group from 50 to 59 years. Most of the patients are from the capital of Amazonas, followed by municipalities in the interior and other states. DCIS is still a major challenge in early detection, and the vast knowledge that has yet to be established in studies of these precursor lesions will add information that will contribute to better conduct these cases.
No conflict of interest has been declared by the author(s).
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Publication History
Article published online:
23 October 2019
© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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Lailson Melgueira Navarro, Larissa Pessoa de Oliveira, Angeli Alexandra Caro Contreras, Sarah Susan Rodrigues Tavares, Renata Maravieski Pareja, Rejaine Ribeiro Vilela, Leandro Castro Breves, Jander Rafael Nogueira da Silva, Hilka Flávia Barra Do Espirito Santo Alves Pereira. HISTORICAL ANALYSIS OF 2003 TO 2013 OF THE CLINIC EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH IN SITU DE BREAST CARCINOMA IN MANAUS - AM. Brazilian Journal of Oncology 2019; 15.
DOI: 10.1055/s-0044-1797939