SURVIVAL OF PATIENTS WITH COLON CANCER WHO UNDERWENT CURATIVE SURGERY AT HOSPITAL NOSSA SENHORA DA CONCEIÇÃO, PORTO ALEGRE / RS

Introduction: The survival of patients with colorectal cancer is directly related to the stage of the disease. Because they present rare symptoms at an early stage, most patients are diagnosed late, thus with advanced disease. As this is a neoplasm of high and increasing incidence worldwide, is necessary to analyze the appropriate therapy and its effectiveness. Objective: To evaluate the survival of patients with stage I, II and III colon cancer who underwent curative surgery at Hospital Nossa Senhora da Conceição (HNSC) between 2010 and 2013. Methods: Cross-sectional retrospective study using electronic medical records as a data source. All patients with stage I, II and III ICD10 C18 who underwent curative intent surgery at the HNSC from 2010 to 2013 were included in the study. Those who had outpatient follow-up of less than 6 months and patients who died due to postoperative complications were excluded. The epidemiological profile, the proposed treatment, disease recurrence and overall 5-year survival were analyzed. Results: The total study sample consisted of 74 patients, with a predominance of females (62.2%). The average age was 69.2 years. The mean follow-up was 62.7 months. Regarding tumor location, 8 (10.8%) were located in the cecum, 10 (13.5%) in the ascending colon, 6 (8.1%) in the hepatic flexure, 1 (1.3%) in the colon. transverse, 2 (2.7%) in the splenic flexure, 5 (6.8%) in the descending colon, 42 (56.8%) in the sigmoid. Regarding TNM staging, 7 (9.5%) patients were stage I, 37 (50%) stage II and 30 (40.5%) stage III. Among the surgical treatment, rectosigmoidectomy was the most performed surgery (58.1%). Adjuvant chemotherapy was performed in 48 patients (64.9%). Of the total number of patients in the study, 9 (12.2%) died, 3 due to cancer. The disease recurred in 7 (9.5%) patients, most of them in stage III (57%), with a mortality of 43% (p = 0.035). The median survival time of patients with recurrence of the disease was 62.8 months and those who did not present was 91.1 months (p = 0.008). The overall 5-year survival was 89.2%. Conclusion: Recurrence of the disease was a factor associated with increased mortality and consequent reduction in long-term survival of patients with colon cancer. Overall 5-year survival of HNSC patients was similar to the literature.

 

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No conflict of interest has been declared by the author(s).

Publication History

Article published online:
23 October 2019