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Semin Musculoskelet Radiol 2025; 29(02): 236-248
DOI: 10.1055/s-0045-1802350
Review Article

Peripheral Spondyloarthritis: Conceptualization and Diagnosis as a Distinct Rheumatologic Subset of Disease

Paul Chroneos
1   Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona
,
David Melville
1   Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona
,
Jeremiah Long
1   Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona
,
Vivek Nagaraja
2   Division of Rheumatology, Mayo Clinic Arizona, Phoenix, Arizona
,
Jonathan A. Flug 
1   Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona
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Abstract

Peripheral spondyloarthritis (pSpA) encompasses multiple entities affecting the musculoskeletal system with classic findings of synovitis, enthesitis, and tenosynovitis. It remains poorly defined when compared with the axial spondyloarthritides due to nonspecific symptoms, ill-defined imaging findings, and lack of specific testable biomarkers. Previous research has tried to distinguish between the two disease entities using clinical presentations, scoring systems, and radiographic findings; however, overlap remains. We summarize the current classification of pSpA, imaging findings, and the distinction between these entities and axial spondyloarthritis.

Keywords

peripheral spondyloarthritis - psoriatic arthritis - enthesitis - axial spondyloarthritis


Publication History

Article published online:
31 March 2025

© 2025. Thieme. All rights reserved.

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