Aims Endoscopic Submucosal Dissection (ESD) is an advanced endoscopic technique that has
emerged as the preferred treatment modality for early gastric cancer (EGC) and is
increasingly adopted in Western countries (1-3). This study evaluates the experience
of a tertiary center in Turkey in employing ESD for the management of gastric neoplastic
lesions [1]
[2]
[3].
Methods Patients with gastric neoplastic lesions who underwent ESD between March 2019 and
March 2023 were included in the study. The rates of en bloc and R0 resection were
investigated. The curability of early gastric cancer (EGC) was evaluated according
to the current guidelines of the Japan Gastroenterological Endoscopy Society. Patients
with a follow-up period of<1 year were excluded from the study.
Results In total, 42 gastric neoplastic lesions from 38 patients were included in the study.
The mean tumour diameter was 26.39 mm (range: 10–75 mm). The success rates of en bloc
and R0 resection were 97.6% and 90.4%, respectively. Curative resection was achieved
in 8/13 (61.5%) patients diagnosed with EGC. The median length of hospital stay was
1 day (range: 1–3 days). Complications occurred postoperatively in 13.1% of the patients.
Recurrence was observed in one patient (2%) at a median follow-up of 18 months (range:
12–57 months).
Conclusions ESD is an effective and safe method for treating gastric neoplastic lesions. The
rate of curative treatment with the ESD method in EGC should be improved.