Efficacy Of Endoscopic Submucosal Dissection In Gastric Neoplastic Lesions: A Single-Center Experience

Aims Endoscopic Submucosal Dissection (ESD) is an advanced endoscopic technique that has emerged as the preferred treatment modality for early gastric cancer (EGC) and is increasingly adopted in Western countries (1-3). This study evaluates the experience of a tertiary center in Turkey in employing ESD for the management of gastric neoplastic lesions [1] [2] [3].

Methods Patients with gastric neoplastic lesions who underwent ESD between March 2019 and March 2023 were included in the study. The rates of en bloc and R0 resection were investigated. The curability of early gastric cancer (EGC) was evaluated according to the current guidelines of the Japan Gastroenterological Endoscopy Society. Patients with a follow-up period of<1 year were excluded from the study.

Results In total, 42 gastric neoplastic lesions from 38 patients were included in the study. The mean tumour diameter was 26.39 mm (range: 10–75 mm). The success rates of en bloc and R0 resection were 97.6% and 90.4%, respectively. Curative resection was achieved in 8/13 (61.5%) patients diagnosed with EGC. The median length of hospital stay was 1 day (range: 1–3 days). Complications occurred postoperatively in 13.1% of the patients. Recurrence was observed in one patient (2%) at a median follow-up of 18 months (range: 12–57 months).

Conclusions ESD is an effective and safe method for treating gastric neoplastic lesions. The rate of curative treatment with the ESD method in EGC should be improved.

 

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Conflicts of Interest

Authors do not have any conflict of interest to disclose.

• References

• 1 Pimentel-Nunes P, Libânio D, Bastiaansen BAJ. et al. Endoscopic submucosal dissection for superficial gastrointestinal lesions: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2022. Endoscopy 2022; 54 (6): 591-622 Epub 2022 May 6
• 2 Ono H, Yao K, Fujishiro M. et al. Guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer (second edition). Dig Endosc 2021; 33 (1): 4-20
• 3 Ono H, Yao K, Fujishiro M, Oda I. et al. Guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer. Dig Endosc 2016; 28 (1): 3-15

Publikationsverlauf

Artikel online veröffentlicht:
27. März 2025