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DOI: 10.1055/s-0045-1807924
Morbidity and mortality profile of Non-Hodgkin lymphoma in pediatric patients over the last 5 years in Brazil
Authors
Introduction: Non-Hodgkin Lymphoma is characterized by the malignancy of lymphatic cells, and is the most common lymphoma in children and adolescents. Advances in treatment for the pediatric age group have impacted cure rates, leading to changes in the morbidity and mortality profiles associated with the disease.
Objective: To analyze the morbidity and mortality profile of pediatric patients with Non-Hodgkin Lymphoma in Brazil over the past five years.
Method: This is a cross-sectional, quantitative, and descriptive study that evaluates hospitalizations and deaths for Non-Hodgkin Lymphoma in the pediatric age group from January 2019 to December 2023 in the Northeast region. Data were collected from the Informatics Department of the Brazilian Unified Health System (DATASUS), through the TABNET tool, using variables such as “color/race,” “state,” “year of service,” “type of service,” “age group,” and “sex,” with statistical analysis performed in Microsoft Excel.
Results: A total of 18,869 cases of Non-Hodgkin Lymphoma were recorded in the Northeast region, of which 13,779 occurred in pediatric patients, representing 15.84% of the national total. Pernambuco stood out with the highest number of hospitalizations (1,289), and the highest concentration of cases was in the 15 to 19 age group (30.55%). Males predominated in hospitalizations (65%), and most patients were of mixed race (66.64%). The majority of the care was emergency (79.01%), and Ceará recorded the highest number of pediatric deaths (21), with the year 2020 showing the highest number of deaths (24).
Conclusion: The research highlights the importance of broadly addressing Non-Hodgkin Lymphoma, considering its significant impact, and the need for public health strategies that encompass the entire population. Additionally, the data presented reinforce the urgency of implementing more robust and innovative early screening campaigns. Those actions are essential to enable early diagnoses and more effective treatments, with the aim of reducing the number of advanced cases and the mortality associated with this pathology.
Corresponding author: Letícia Bezerra de Almeida (e-mail: leticiabezerradealmeida@hotmail.com).
No conflict of interest has been declared by the author(s).
Publication History
Article published online:
06 May 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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Letícia Bezerra de Almeida, Sofia Fernandes Silva, Lorena Galvão de Oliveira, Gisele dos Santos Rodrigues, Marjorie Karla Medeiros Menezes, Lívia Monteiro Marques Morais, Virna Araújo Moreira da Nóbrega, Lettícia Tenório Cavalcanti, André Gustavo de Lima Santana, Gabriel Monteiro Marques Morais, Iádylla Barbosa Alves Dantas, Felipe Nathan Ribeiro da Costa, Mariana de Almeida Ferraz, Flávio Antônio Bezerra de Araújo Filho, Arthur Nóbrega Rodrigues de Lima, Henrique Fialho Carneiro Braga Costa, Bruno Varela Fernandes, Matheus Henrique Marinho de Gouveia, Hiago de Freitas Macedo, Larissa de Pontes Costa Abreu, Carla Vitória Brito dos Santos, Paulo Vinícios Morais Alexandre, Giulia Di Cedico Paranhos. Morbidity and mortality profile of Non-Hodgkin lymphoma in pediatric patients over the last 5 years in Brazil. Brazilian Journal of Oncology 2025; 21.
DOI: 10.1055/s-0045-1807924