ABSTRACT
A majority of patients diagnosed with non-small cell lung cancer (NSCLC) will have
advanced disease at diagnosis. In the past, systemic therapy (chemotherapy) has demonstrated
only slight improvement in survival, hence, practitioners were reluctant to refer
patients for cytotoxic therapy. In the past few years, newer chemotherapeutic agents,
with increased activity against NSCLC, have been shown to significantly improve median
and 1-year survival rates and improve quality of life. Although advanced NSCLC is
considered incurable disease, it is, however, potentially treatable disease. This
chapter will address the evidence regarding currently available therapies for patients
with advanced stage NSCLC.
KEYWORD
Non-small cell lung cancer - advanced stage - chemotherapy