Objective: The evolution of the senior author's (HD Jho) surgical experience on endoscopic endonasal
transsphenoidal pituitary surgery is reviewed in order to introduce a standardized
surgical technique for pituitary endoscopy. Methods: The progressive evolution of the surgical technique and the development of surgical
instrumentation in transsphenoidal endoscopy is reviewed based upon the experience
of more than 150 operations performed by the senior author between the years 1993
and 1998. Results: An endoscope was used to assist visualization during conventional microscopic surgery
in the first four cases (endoscope-assisted microsurgery). Subsequently, endonasal
pituitary endoscopy was performed via a nostril. When the endonasal route was adopted,
it eliminated the use of a transsphenoidal retractor. The use of vasoconstrictors
and any form of nasal packing was discovered to be unnecessary. The inferior margin
of the middle turbinate was such a consistent surgical landmark leading to the sella
that the use of an intraoperative fluoroscopic C-arm was also eliminated. The adoption
of a septal breaker, variously angled suction cannulas and suction-coagulators has
made the operation cleaner, easier and faster. As experience increased, the operation
time progressively shortened and mucosal trauma became minimal. The median patient
hospital stay was one night and postoperative discomfort was noted to be minimal.
Conclusions: The evolution of the senior author's endoscopic pituitary surgery is reported with
a description of our current standardized surgical technique.
Key words:
Acromegaly - Cushing's Disease - Endoscopy - Pituitary Adenoma - Pituitary Gland -
Prolactinoma - Transsphenoidal Surgery
References
1
Carrau R L, Jho H D, Ko Y.
Transnasal-transsphenoidal endoscopic surgery of the pituitary gland.
Laryngoscope.
1996;
106
914-918
2
Jho H D.
Endoscopic endonasal pituitary surgery: Technical aspects.
Contemporary Neurosurgery.
1997;
19 (6)
1-7
3 Jho H D, Carrau R L, Ko Y. Endoscopic pituitary surgery. In: Wilkins RH, Rengachary
SS (eds). Neurosurgical operative atlas Baltimore: Williams & Wilkins vol. 5 (1) 1996:
1-12
4
Jho H D, Carrau R L.
Endoscopy assisted transsphenoidal surgery for pituitary adenoma. Technical note.
Acta Neurochir (Wien).
1996;
138
1416-1425
5
Jho H D, Carrau R L.
Endoscopic endonasal transsphenoidal surgery: Experience with 50 patients.
J Neurosurg.
1997;
87
44-51
6
Jho H D, Carrau R L, McLaughlin M L, Somaza S C.
Endoscopic transsphenoidal resection of a large chordoma in the posterior fossa.
Acta Neurochir (Wien).
1997;
139
343-348
7
Jho H D, Carrau R L, Ko Y, Daly M.
Endoscopic pituitary surgery: An early experience.
Surg Neurol.
1997;
47
213-223
8
Stammberger H.
Endoscopic endonasal surgery - concepts in treatment of recurring rhinosinusitis.
Part II. Surgical technique.
Otolaryngol Head Neck Surg.
1986;
94
147-156
9
Cappabianca P, Alfieri A, de Divitiis E.
Endoscopic endonasal transsphenoidal approach to the sella: Towards functional endoscopic
pituitary surgery (FEPS).
Minim Invas Neurosurg.
1998;
41
66-73
10
Gamea A, Fathi M, EL-Guindy A.
The use of the rigid endoscope in trans-sphenoidal pituitary surgery.
J Laryngol Otol.
1994;
108
19-22
11
Guiot G, Rougerie J, Fourestler A, Fournier A, Comoy C, Vulmiere J, Groux R.
Une nouvelle technique endoscopique. Exploration endoscopiques intracraniennes.
La Presse Medicale.
1963;
71
1225-1228
12
Heilman C B, Shucart W A, Rebeiz E E.
Endoscopic sphenoidotomy approach to the sella.
Neurosurgery.
1997;
41
602-607
13
Helal M Z.
Combined micro-endo trans-sphenoid excisions of pituitary macroadenomas.
Eur Arch Otorhinolaryngol.
1995;
252 (3)
186-189
14
Jankowski R, Auque J, Simon C, Marchal J C, Hepner H, Wayoff M.
Endoscopic pituitary tumor surgery.
Laryngoscope.
1992;
102
198-202
15
Rodziewicz G S, Kelly R T, Kellman R M, Smith M V.
Transnasal endoscopic surgery of the pituitary gland: Technical note.
Neurosurgery.
1996;
39
189-193
16
Sethi D S, Pillay P K.
Endoscopic management of lesions of the sella turcica.
J Laryngol Otol.
1995;
109 (10)
956-962
17
Shikani A H, Kelly J H.
Endoscopic debulking of a pituitary tumor.
Am J Otolaryngol.
1993;
14 (4)
254-256
18
Wurster C F, Smith D E.
The endoscopic approach to the pituitary gland (letter).
Arch Otolaryngol Head Neck Surg.
1994;
120
674
19
Yaniv E, Rappaport Z H.
Endoscopic transseptal transsphenoidal surgery for pituitary tumors.
Neurosurgery.
1997;
40
944-946
20 Landolt A M. History of transsphenoidal pituitary surgery. In: Landolt AM, Vance
ML, Reilly PL (eds). Pituitary adenomas Churchill Livingstone 1996: 307-314
21
Griffith H B, Veerapen R.
A direct transnasal approach to the sphenoid sinus. Technical Note.
Neurosurg.
1987;
66
140-142
22
Cooke R S, Jones R AC.
Experience with the direct transnasal transsphenoidal approach to the pituitary fossa.
Br J Neurosurg.
1994;
8
193-196
Corresponding Author
H D Jho,M. D., Ph. D
Minimally Invasive Innovative Microneurosurgery Department of Neurological Surgery UPMC, Presbyterian
Suite B-400 200 Lothrop Street Pittsburgh Pennsylvania 15213 USA
Telefon: Phone:+1-412-647-0986
Fax: Fax:+1-412-647-0989
eMail: E-mail:hdjho@neuronet.pitt.edu