Clinical and Laboratory Diagnosis of Deep Vein Thrombosis: New Cost-Effective Strategies

Henri Bounameaux; Arnaud Perrier; Philip S. Wells

doi:10.1055/s-2001-14540

Seminars in Vascular Medicine, Inhaltsverzeichnis

Semin Vasc Med 2001; 01(1): 039-042
DOI: 10.1055/s-2001-14540

Clinical and Laboratory Diagnosis of Deep Vein Thrombosis: New Cost-Effective Strategies

Henri Bounameaux¹ , Arnaud Perrier² , Philip S. Wells³

¹Division of Angiology and Hemostasis, Medical Clinic, University Hospital of Geneva, Geneva, Switzerland
²Department of Internal Medicine, Medical Clinic, University Hospital of Geneva, Geneva, Switzerland
³Division of Hematology, Ottawa Civic Hospital, Ottawa, Canada

Abstract

ABSTRACT

Diagnosis of deep vein thrombosis (DVT) has been made easier, less invasive, and somewhat safer over the past 2 decades. This has been due mainly to the development of venous compression ultrasonography (US). The prevalence of the disease in patients clinically suspected of DVT has steadily decreased during the past 10 years, likely as a consequence of the accurate noninvasive test, ultrasound imaging. This has led to the development of diagnostic tools that aim at reducing the number of unnecessary US exams. These include clinical probability assessment and fibrin D-dimer. Several strategies combining these tools have been validated in large-outcome studies and compared in a formal cost-effectiveness analysis. The results indicate that they should now be implemented in daily practice, taking into account local facilities and expertise.

KEYWORD

Deep vein thrombosis - venous compression ultrasonography - D-dimer

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Referenzen

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