ABSTRACT
Osteoarthritis, based on either cartilage injury or degeneration, is a leading cause
of disability in the United States. Over the last several decades, much progress has
been made in understanding cartilage injury and repair. Magnetic resonance (MR) imaging,
with its unique ability to noninvasively image and characterize soft tissue, has shown
promise in assessment of cartilage integrity. In addition to standard MR imaging methods,
MR imaging contrast mechanisms under development may reveal detailed information regarding
the physiology and morphology of cartilage. MR imaging will play a crucial role in
assessing the success or failure of therapies addressing cartilage injury and degeneration.
KEYWORD
Osteoarthritis - articular cartilage - magnetic resonance imaging