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Int J Sports Med 2002; 23(3): 174-177
DOI: 10.1055/s-2002-23175
Physiology and Biochemistry
© Georg Thieme Verlag Stuttgart · New York

Alactic Anaerobic Performance in Subjects with Sickle Cell Trait and Hemoglobin AA

O.  Hue1 , M.  E.  Julan2 , S.  Blonc1 , St.  Martin2 , C.  Hertogh1 , L.  Marlin1 , C.  Pallud1 , D.  Le Gallais3
  • 1Laboratoire ACTE, Université des Antilles et de la Guyane, Campus de Fouillole, Pointe à Pitre Cedex, France
  • 2Centre Intégré de la Drépanocytose ”Guy Mérault“, CHU, Pointe à Pitre, France
  • 3Laboratoire Sport, Performance, Santé, UE 147, UFR-STAPS, Montpellier, France
Further Information

Publication History

August 25, 2001

Publication Date:
26 March 2002 (online)

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Abstract

The aim of the present study was to assess the performance of subjects with sickle cell trait (SCT) during brief and explosive exercise involving mainly anaerobic metabolism. One hundred and ninety-six black subjects underwent SCT screening, which revealed the presence of 16 subjects with SCT and 180 subjects with normal hemoglobin (HbAA). All subjects performed four tests: 1) a 100-m sprint, 2) a long-jump, 3) a Leger-Boucher shuttle test and 4) a jump-and-reach test. A control group (n = 18) selected from the 180 subjects with HbAA was matched according to the sex, age, weight and height of the SCT subjects (SCTs). The performances of the SCTs (n = 16) were compared with those of the control group. The performances were similar between the SCTs and control group for the sprint test, long-jump and the Leger-Boucher shuttle test. There was, however, a significant difference for the jump-and-reach test between the two groups: the SCTs (i. e., males plus females, and males and females considered separately) reached a significantly greater height (p < 0.05) than the matched subjects of the control group (63.7 ± 3.6 vs. 58.6 ± 3.1 cm, 72.3 ± 3.9 vs. 67.1 ± 2.4 cm and 52.7 ± 3.2 vs. 45.3 ± 2.0 cm for SCTs versus non-SCTs, for the group, the males and the females, respectively). The results of the present study suggest that the performance of brief and explosive exercise may be enhanced by HbS.

Key words

Sickle cell trait - anaerobic performance - anaerobic metabolism - jump-and-reach test

References

  • 1 Bilé A, Le Gallais D, Mercier J, Bogui P, Préfaud C. Sickle cell trait in Ivory Coast athletic throw and jump champions, 1956 - 1995.  Int J Sports Med. 1998;  19 215-219
    PubMedGoogle Scholar
  • 2 BiIé A, Le Gallais D, Mercier B, Martinez P, Ahmaidi S, Préfaut C. Anaerobic exercise components during the force-velocity test in sickle cell trait.  Int J Sports Med. 1996;  17 254-258
    PubMedGoogle Scholar
  • 3 Boutros-Toni F, Dosso Y, Freminet A, Leclerc L, Poyart C. Réactions cardio-respiratoires et métaboliques a` un exercise, sous-maximal de sujets africains porteurs du trait drépanocytaire.  Nouv Rev Fr Hématol. 1980;  22 37-45
    PubMedGoogle Scholar
  • 4 Davies C TM, Young K. Effects of external loading on short term power output in children and young male adults.  Eur J Appl Physiol.. 1984;  52 351-354
    CrossrefPubMedGoogle Scholar
  • 5 Diggs L W, Flowers E. High school athletes with sickle cell trait (Hb, A/S).  J Natl Med Ass. 1976;  68 492-493
    PubMedGoogle Scholar
  • 6 Edington G M, Lehman H. Expression of the sickle cell gene in Africa.  Br Med J. 1955;  1 1308-1311
    PubMedGoogle Scholar
  • 7 Ewing P C. Death of an athlete with sickle cell trait.  World Med News. 1974;  15 38-44
    PubMedGoogle Scholar
  • 8 Freund H, Lonsdorfer J, Oyono-Enguele S, Lonsdorfer A, Bogui P. Lactate exchange and removal. Ability in sickle cell patients and in untrained and trained healthy humans .  J AppI Physiol.. 1992;  73 2580-2587
    PubMedGoogle Scholar
  • 9 Gozal D, Thiriet P, Mbala E. , Wouassi D, Gelas H, Geyssant A, Lacour JR.  Effect of different modalities of exercise performance in subjects with sickle cell trait. Med Sci Sports Exerc. 1992;  24 1325-1331
    PubMedGoogle Scholar
  • 10 Hertogh C, Micallef J P, Mercier J. Maximal anaerobic power in teenagers (transversal study). (Puissance anaérobie maximale chez l’adolescent (étude transversale).  Sci Sports. 1992;  7 207-213
    PubMedGoogle Scholar
  • 11 Huisman T HJ. Sickle cell anemia as a syndrome: a review of diagnostic features.  Am J Hematol. 1979;  6 173-184
    PubMedGoogle Scholar
  • 12 Hutinger P W. Differences in speed between American Negro and White children in performance of the 35-yard dashes.  Res Q. 1959;  30 366-368
    PubMedGoogle Scholar
  • 13 Jones N L, McCartney N, Graham T, Spriet L, Kowalschuck J M, Heigenhauser G JF, Sutton J R. Muscle performance and metabolism in maximal isokinetic cycling at slow and fast speed.  J Appl Physiol. 1985;  59 132-136
    PubMedGoogle Scholar
  • 14 Jones S R, Binder R A, Donowho E M. Sudden death in sickle cell trait.  N Engl J Med. 1970;  282 323-325
    PubMedGoogle Scholar
  • 15 Kark J A. Posey DM, Schumacher HR, Ruehle CJ: Sickle cell trait as a risk factor for sudden death in physical training.  N Engl J Med. 1987;  317 781-787
    PubMedGoogle Scholar
  • 16 Kark J A, Ward F T. Exercise and hemoglobin S.  Hematology. 1994;  31 181-225
    PubMedGoogle Scholar
  • 17 Le Gallais D, Bile¿ A, Mercier J, Paschel M, Tonellot J L, Dauverchain J. Exercise-induced death in sickle cell trait: role of aging, training and deconditioning.  Med Sci Sports Exerc. 1996;  28 541-544
    PubMedGoogle Scholar
  • 18 Le Gallais D, Lonsdorfer J, Buguet A, Daures J P, Mercier J, Macabies J, Préfaut C. Aptitude physique des porteurs du trait drépanocytaire.  Sci Sports. 1987;  2 269-277
    PubMedGoogle Scholar
  • 19 Le Gallais D, Pre¿faut C, Dulat C, Macabies J, Lonsdorfer J. Sickle cell trait in Ivory Coast athletic champions, 1956 - 1989.  Int J Sports Med. 1991;  12 509-510
    PubMedGoogle Scholar
  • 20 Le Gallais D, Préfaut C, Mercier J, Bile¿ A, Bogui P, Lonsdorfer J. Sickle cell trait as a limiting factor for high-level performance in a semimarathon.  Int J Sports Med. 1994;  15 339-402
    PubMedGoogle Scholar
  • 21 Le Gallais D, Lonsdorfer J, Bogui P, Mercier J, Macabies J, Préfaut J. Trait drépanocytaire (AS) et performance en course de vitesse, de résistance et d’endurance.  Sci Sports. 1989;  4 249-251
    PubMedGoogle Scholar
  • 22 Le Gallais D, Bogui P, Dulat C, Arra J, Préfaut C, Lonsdorfer J. Participation d’adolescents drépanocytaires AS a` une course de 3000 mètres.  Sci Sports. 1989;  4 123-128
    PubMedGoogle Scholar
  • 23 Le¿ger L, Boucher R. An indirect continuous running multistage field test: the Université de Montréal track test.  Can J Sport Sci. 1980;  5 77-84
    PubMedGoogle Scholar
  • 24 Lonsdorfer J, Bogui P, Boutros-Toni F, Dosso Y, Lonsdorfer A, Otayeck A, Pigerias B, Valery J, Cabannes R. Cardio-respiratory physiopathology in HbS hemoglobinopathies. (Physiopathologie cardio-respiratoire dans les hémoglobkopathies à hbS).  Méd Trop. 1986;  22 31-46
    PubMedGoogle Scholar
  • 25 Mercier B, Mercier J, Préfaut C. Blood lactate increase during the force-velocity exercise test.  Int J Sports Med. 1991;  12 17-20
    PubMedGoogle Scholar
  • 26 Milne C, Seefeldt V, Reuschlein P. Relationship between grade, sex, race, and motor performance in young children.  Res Q. 1976;  47 726-730
    PubMedGoogle Scholar
  • 27 Murphy J R. Sickle cell hemoglobin (HbAS) in black football players.  JAMA. 1973;  225 981-982
    CrossrefPubMedGoogle Scholar
  • 28 Ponthieux , NA , Barker D G. Relationship between race and physical fitness.  Res Q. 1965;  36 468-472
    PubMedGoogle Scholar
  • 29 Robinson J R, Stone W J, Asendorf A C. Exercise capacity of black sickle cell trait males.  Med Sci Sports Exerc. 1976;  8 244-245
    PubMedGoogle Scholar
  • 30 Samson J, Yerles M. Racial differences in sports performance.  Can J Sports Sci. 1988;  13 109-116
    PubMedGoogle Scholar
  • 31 Sayers S P, Harackiewicz D V, Harman E A, Frykman P N, Rosenstem M T. Cross-validation of three jump power equations.  Med Sci Sports Exerc. 1999;  31 572-577
    CrossrefPubMedGoogle Scholar
  • 32 Weisman I M, Zeballos R J, Johnson B D. Cardiopulmonary and gas exchange responses to acute streneous exercise at 1270 meters in sickle cell trait.  Am J Med. 1988;  84 377-383
    CrossrefPubMedGoogle Scholar
  • 33 Weisman I M, Zeballos R J, Martin T W, Johnson B D. Effect of army basic training in sickle cell trait.  Arch Intern Med. 1988;  148 1140-1148
    CrossrefPubMedGoogle Scholar

O. Hue

Laboratoire ACTE · Université des Antilles et de la Guyane

Campus de Fouillole · 97159 Pointe à Pitre Cedex · France

Email: HueO@wanadoo.fr

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