1,3-Dipolar Cycloaddition Reactions of Nitrones to Prop-1-ene-1,3-sultone

Li Tian; Guo-Yan Xu; Yong Ye; Lun-Zu Liu

doi:10.1055/s-2003-40201

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1,3-Dipolar Cycloaddition Reactions of Nitrones to Prop-1-ene-1,3-sultone

Li Tian, Guo-Yan Xu, Yong Ye, Lun-Zu Liu*
State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, P. R. China
e-Mail: tian_lili@eyou.com;

Abstract

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Abstract

The reaction of prop-1-ene-1,3-sultone (1) with a variety of nitrones 2 afforded novel [3+2] cycloaddition products 3, 4, and 5 in good yield. Excellent regio- and stereoselectivity were achieved in the cycloaddition reaction with phenylnitrones.

Key words

cycloaddition - nitrone - sultone - regioselectivity - stereoselectivity

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References

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