Interventionelle Verfahren in der nuklearmedizinischen Nierenfunktionsdiagnostik

Zusammenfassung

Die Isotopennephrographie stellt ein sehr sensitives Verfahren dar, das auch geringe Veränderungen der Organfunktion erfasst. Durch interventionelle Maßnahmen, insbesondere durch pharmakologische Intervention, kann vor allem die Spezifität der Methode für bestimmte klinische Fragestellungen wesentlich erhöht werden. Der vorliegende Übersichtsartikel fasst den gegenwärtigen Stand der interventionellen Nierenfunktionsdiagnostik bei der Abklärung einer Hypertonie und der Beurteilung von Harnabflussstörungen zusammen. Es werden sowohl methodische Aspekte wie Durchführung der Untersuchung, Auswerteverfahren und mögliche Fehlerquellen als auch die klinische Wertigkeit der Verfahren besprochen.

Abstract

Radionuclide kidney function studies are very sensitive measures and renography allows to detect even slight alterations of organ function. Interventions, especially pharmacologic stress may permit observation of variations in kidney function which are typical for a disease. Therefore in clinical routine, pharmacologic intervention augments the specificity of the test significantly. This review article summarizes the state of the art in the application of interventional renography in the question of hypertension and urinary outflow obstruction. Methodological aspects as practice and protocols, data analysis and diagnostic parameters and limitations and pitfalls are described. The diagnostic potential for the clinical indications is discussed.

Schlüsselwörter

Nierenfunktionsszintigraphie - Hypertonie - Harnabflussstörung

Key words

Renography - hypertension - urinary outflow obstruction

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