Abstract
Palladacycles 1 and 2 , derived from 4,4′-dichlorobenzophenone and 4-hydroxyacetophenone oximes, respectively,
are very efficient and versatile pre-catalysts for a wide range of carbon-carbon bond
coupling reactions such as, Mizoroki-Heck, Suzuki-Miyaura, Stille, Ullmann-type, Sonogashira,
sila-Sonogashira, Glaser and acylation of alkynes under very low loading conditions
in air and either in organic or aqueous solvents, employing reagent-grade chemicals.
High yielding, general, and practical procedures for the palladium-catalyzed Mizoroki-Heck,
Suzuki-Miyaura, Ullmann-type, Sonogashira and sila-Sonogashira reactions are described.
Key words
cross-coupling - palladacycles - Heck reaction - biaryls - alkynes
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