Int J Sports Med 2005; 26(7): 513-517
DOI: 10.1055/s-2004-821223
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Effects of Acute Salbutamol Intake During a Wingate Test

K. Collomp1 , 2 , B. Le Panse1 , H. Portier1 , A.-M. Lecoq3 , C. Jaffre1 , H. Beaupied1 , O. Richard4 , L. Benhamou1 , D. Courteix1 , J. De Ceaurriz2
  • 1LPM-IPROS, Faculté des Sports, Orléans, France
  • 2LNDD, Chatenay-Malabry, France
  • 3Service EFR, Hôpital de la Madeleine, Orléans, France
  • 4LMCN, UFR Sciences, Orléans, France
Further Information

Publication History

Accepted after revision: May 20, 2004

Publication Date:
27 September 2004 (online)

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Abstract

To investigate the impact of acute salbutamol intake on performance and selected hormonal and metabolic variables during supramaximal exercise, 13 recreational male athletes performed two 30-second Wingate tests after either placebo (PLA, lactose) or salbutamol (SAL, 4 mg) oral administration, according to a double-blind and randomized protocol. Blood samples collected at rest, end of the Wingate test, recovery (5, 10, 15 min) were tested for growth hormone (GH), insulin (INS), blood glucose (GLU), and lactate determination. We found the peak and mean power performed significantly increased after SAL vs. PLA (PPSAL: 896 ± 46; PPPLA: 819 ± 57 W; MPSAL: 585 ± 27; MPPLA: 534 ± 35 W, p < 0.05), whereas no change was observed in the fatigue index. Blood glucose and INS were significantly increased by SAL at rest, at the end of the Wingate test, and during the 5 first minutes of recovery (p < 0.05). Plasma GH was significantly decreased by SAL (p < 0.05) during the recovery whereas end-exercise and recovery blood lactate tended but were not significantly increased after SAL vs. PLA. From these data, acute salbutamol intake at therapeutical dosage did appear to improve peak power and mean power during a supramaximal exercise, but the mechanisms involved need further investigation.

References

Katia Collomp

Laboratoire de la Performance Motrice, Faculté du Sport et de l'Education Physique

Rue de Vendôme, BP 6237

45062 Orléans Cedex 2

France

Phone: + 0238417178

Fax: + 02 38 41 72 60

Email: katia.collomp@univ-orleans.fr