RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000068.xml
PDF herunterladen
Semin intervent Radiol 2003; 20(4): 279-292
DOI: 10.1055/s-2004-828939
DOI: 10.1055/s-2004-828939
Radiofrequency Ablation of Hepatic Tumors
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
20. Juli 2004 (online)
ABSTRACT
Minimally invasive image-guided procedures such as radiofrequency (RF) ablation, high intensity ultrasonography and microwave, as well as injectable therapies such as ethanol are becoming ever more useful options for the treatment of liver tumors. In this review, we focus initially on current clinical practice and research on radiofrequency ablation for both primary hepatocellular carcinoma and hepatic metastases from colon, breast, and neuroendocrine tumors. We then examine various treatment approaches such as laparoscopy and laparotomy, as well as the use of adjuvant therapies and imaging guidance. Finally, complications and current limitations of therapy are discussed.
KEYWORDS
Tumor ablation - radiofrequency - ablation - hepatic tumors
REFERENCES
- 1 Goldberg S N, Liveraghi T, Solbiati L, Gazelle G S. In situ ablation of focal hepatic neoplasms. In: Gazelle GS, Saini S, Mueller PR, eds. Hepatobiliary and Pancreatic Radiology:
Imaging and Intervention New York: Thieme, 1997: 470-502
Reference Ris Wihthout Link
- 2 Dupuy D E, Goldberg S N. Image-guided radiofrequency tumor ablation: challenges and opportunities-part II. J Vasc Interv Radiol . 2001; 12 1135-1148
- 3 Goldberg S N, Dupuy D E. Image-guided radiofrequency tumor ablation: Challenges and opportunities-Part I. J Vasc Interv Radiol . 2001; 12 1021-1032
- 4 Asahara T, Nakahara H, Fukuda T. et al . Percutaneous microwave coagulation therapy for hepatocellular carcinoma. Hiroshima J Med Sci . 1998; 47 151-155
- 5 Buscarini L, Buscarini E, Di Stasi M, Vallisa D, Quaretti P, Rocca A. Percutaneous radiofrequency ablation of small hepatocellular carcinoma: long-term results. Eur Radiol . 2001; 11 914-921
- 6 Curley S A, Izzo F, Ellis L M, Nicolas Vauthey J, Vallone P. Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg . 2000; 232 381-391
- 7 Lu M D, Chen J W, Xie X Y. et al . Hepatocellular carcinoma: US-guided percutaneous microwave coagulation therapy. Radiology . 2001; 221 167-172
- 8 Solbiati L, Ierace T, Tonolini M, Osti V, Cova L. Radiofrequency thermal ablation of hepatic metastases. Eur J Ultrasound . 2001; 13 149-158
- 9 Gillams A R, Lees W R. Survival after percutaneous, image-guided, thermal ablation of hepatic metastases from colorectal cancer. Dis Colon Rectum . 2000; 43 656-661
- 10 Shibata T, Niinobu T, Ogata N, Takami M. Microwave coagulation therapy for multiple hepatic metastases from colorectal carcinoma. Cancer . 2000; 89 276-284
- 11 Beppu T, Doi K, Ishiko T, Hirota M, Egami H, Ogawa M. Efficacy of local ablation therapy for liver metastasis from colorectal cancer-radiofrequency ablation and microwave coagulation therapy. Nippon Geka Gakkai Zasshi . 2001; 102 390-397
- 12 Vogl T, Mack M, Straub R. et al . Thermal ablation of liver metastases. Current status and prospects. Radiologe . 2001; 41 49-55
- 13 Mack M G, Straub R, Eichler K. et al . Percutaneous MR imaging-guided laser-induced thermotherapy of hepatic metastases. Abdom Imaging . 2001; 26 369-374
- 14 Zagoria R J, Chen M Y, Kavanagh P V, Torti F M. Radio frequency ablation of lung metastases from renal cell carcinoma. J Urol . 2001; 166 1827-1828
- 15 Kim T S, Lim H K, Lee K S. et al . Imaging-guided percutaneous radiofrequency ablation of pulmonary metastatic nodules caused by hepatocellular carcinoma: preliminary experience. AJR Am J Roentgol . 2003; 181 491-494
- 16 Pautler S E, Pavlovich C P, Mikityansky I. et al . Retroperitoneoscopic-guided radiofrequency ablation of renal tumors. Can J Urol . 2001; 8 1330-1333
- 17 Pavlovich C P, Walther M M, Choyke P L. et al . Percutaneous radio frequency ablation of small renal tumors: initial results. J Urol . 2002; 167 10-15
- 18 Murphy D P, Gill I S. Energy-based renal tumor ablation: a review. Semin Urol Oncol . 2001; 19 133-140
- 19 Dupuy D E, Monchik J M, Decrea C, Pisharodi L. Radiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy. Surgery . 2001; 130 971-977
- 20 Jeffery S S, Birdwell R L, Ikeda D M. Radiofrequency ablation of breast cancer: first report of an emerging technology. Arch Surg . 1999; 134 1064-1068
- 21 Woertler K, Vestring T, Boettner F, Winkelmann W, Heindel W, Lindner N. Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47 patients. J Vasc Interv Radiol . 2001; 12 717-722
- 22 Lindner N J, Ozaki T, Roedl R, Gosheger G, Winkelmann W, Wortler K. Percutaneous radiofrequency ablation in osteoid osteoma. J Bone Joint Surg Br . 2001; 83 391-396
- 23 Witt J D, Hall-Craggs M A, Ripley P, Cobb J P, Bown S G. Interstitial laser photocoagulation for the treatment of osteoid osteoma. J Bone Joint Surg Br . 2000; 82 1125-1128
- 24 Gangi A, Dietemann J L, Clavert J M. et al . Treatment of osteoid osteoma using laser photocoagulation. Appropos of 28 cases. Rev Chir Orthop Reparatrice Appar Mot . 1998; 84 676-684
- 25 Hargreaves G M, Adam R, Bismuth H. Results after nonsurgical local treatment of primary liver malignancies. Langenbecks Arch Surg . 2000; 385 185-193
- 26 Goldberg S N, Gazelle G S, Mueller P R. Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, technqiues, and diagnostic imaging guidance. Am J Radiol . 2000; 174 323-331
- 27 Gazelle G S, Goldberg S N, Solbiati L, Livaraghi T. Tumor ablation with radiofrequency energy. Radiology . 2000; 217 633-646
- 28 Honda N, Guo Q, Uchida H, Ohishi H, Hiasa Y. Percutaneuous hot saline injection therapy for hepatic tumors: an alternative to percutaneous ethanol injection therapy. Radiology . 1994; 190 53-57
- 29 Goldberg S N, Stein M, Gazelle G S, Sheiman R G, Kruskal J B, Clouse M E. Percutaneous radiofrequency tissue ablation: optimization of pulsed-RF technique to increase coagulation necrosis. J Vasc Interv Radiol . 1999; 10 907-916
- 30 Solbiati L, Livraghi T, Goldberg S N, Ierace T, DellaNoce M, Gazelle G S. Percutaneous radiofrequency ablation of hepatic metastases from colorectal cancer: long term results in 117 patients. Radiology . 2001; 221 159-166
- 31 Goldberg S N, Solbiati L, Hahn P F. et al . Large-volume tissue ablation with radiofrequency by using a clustered, internally-cooled electrode technique: laboratory and clinical experience in liver metastases. Radiology . 1998; 209 371-379
- 32 Rossi S, Buscarini E, Garbagnati F. Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR Am J Roentgenol . 1998; 170 1015-1022
- 33 Dupuy D E, Goldberg S N, Gazelle G S, Rosenthal D I. Cooled-tip radio-frequency ablation in the vertebral body: temperature distribution in the spinal canal (abst). Radiology . 1997; 807(P) 330
- 34 Livraghi T, Goldberg S N, Meloni F, Solbiati L, Gazelle G S. Hepatocellular carcinoma: comparison of efficacy between percutaneous ethanol instillation and radiofrequency. Radiology . 1999; 210 655-661
- 35 Dodd III D G, Soulen M C, Kane R A. et al . Minimally invasive treatment of malignant hepatic tumors: at the threshold of a major breakthrough. Radiographics . 2000; 20 9-27
- 36 Gazelle G S, Goldberg S N, Solbiati L, Livraghi T. Tumor ablation with radiofrequency energy. Radiology . 2000; 217 6333-6346
- 37 McGahan J P, Dodd III D G. Radiofrequency ablation of the liver: current status. AJR Am J Roentgenol . 2001; 176 3-16
- 38 Tuttle T. Hepatectomy for noncolorectal liver metastases. In: Curley SA, ed. Liver Cancer New York: Springer 1991: 201-211
Reference Ris Wihthout Link
- 39 Curley S A, Izzo F. Radiofrequency ablation of primary and metastatic hepatic malignancies. Int J Clin Oncol . 2002; 7 72-81
- 40 Lambert L A, Colacchio T A, Barth Jr J R. Interval hepatic resection of colorectal metastases improves patient selection. Arch Surg . 2000; 135 473-479
- 41 Liveraghi T, Solbiati L, Meloni F, Ierace T, Goldberg S N, Gazelle G S. Percutaneous radiofrequency ablation of liver metastases in potential candidates for resection: the “test-of-time” approach Cancer . 2003; 97(12) 3027-3035
- 42 Livraghi T, Lazzaroni S, Meloni F. Radiofrequency thermal ablation of hepatocellular carcinoma. Eur J Ultrasound . 2001; 13 159-166
- 43 Livraghi T, Meloni F, Goldberg S N, Lazzaroni S, Solbiati L, Gazelle G S. Hepatocellular carcinoma: radiofrequency ablation of medium and large lesions. Radiology . 2000; 214 761-768
- 44 Curley S A, Izzo F, Delrio P. Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients. Ann Surg . 1999; 230 1-8
- 45 Rossi S, Distasi M, Buscarini E. Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. AJR Am J Roentgenol . 1996; 167 759-768
- 46 Ikeda M, Okada S, Uena H. et al . Radiofrequency ablation and percutaneous ethanol injection in patients with small hepatocellular carcinoma: a comparative study. Jpn J Clin Oncol . 2001; 31 322-326
- 47 Lencioni R A, Allgaier H, Cioni D. et al . Small hepatocellular carcinoma in cirrhosis: randomized comparison of radio-frequency thermal ablation versus percutaneous ethanol injection. Radiology . 2003; 228 235-240
- 48 Livraghi T. Guidelines for treatment of liver cancer. Eur J Ultrasound . 2001; 13 167-176
- 49 Fontana R J, Hamidullah H, Nghiem H. et al . Percutaneous radiofrequency thermal ablation of hepatocellular carcinoma: a safe and effective bridge to liver transplantation. Liver Transpl . 2002; 8(12) 1165-1174
- 50 American Cancer Society. Cancer facts and figures. Washington, DC: American Cancer Society; 2002
Reference Ris Wihthout Link
- 51 Bengstsson G, Carlsson G, Hafstrom L, Jonsson P-E. Natural history of patients with untreated liver metastses from colorectal cancer. Am J Surg . 1981; 141 586-589
- 52 Hughes K S, Rosenstein R B, Songhorabodi S. et al . Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of long-term survivors. Dis Colon Rectum . 1988; 31 1-4
- 53 De Baere T, Elias D, Dromain C. et al . Radiofrequency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. AJR Am J Roentgenol . 2000; 175 1619-1625
- 54 Adson M A. Resection of liver metastases-when is it worthwhile?. World J Surg . 1987; 11 511-520
- 55 Elias D, Lasser P H, Montrucolli D. et al . Hepatectomy for liver metastases from breast cancer. Eur J Surg Oncol . 1995; 21 510-513
- 56 Siperstein A E, Rogers S J, Hansen P D. et al . Laparoscopic thermal ablation of hepatic neuroendocrine tumor metastases. Surgery . 1997; 122 1147-1155
- 57 Livraghi T, Goldberg S N, Solbitati L. et al . Percutaneous radiofrequency ablation of liver metastases from breat cancer: initial experience in 24 patients. Radiology . 2001; 220 145-149
- 58 Henn A R, Levine E A, McNulty W, Zagoria R J. Percutaneous radiofrequency ablation of hepatic metastases for symptomatic relief of neuroendocrine syndromes. AJR Am J Roentgenol . 2003; 181 1005-1010
- 59 Que F G, Nagorney D M, Batts K P. et al . Hepatic resection for metastatic neuroendocrine carcinomas. Am J Surg . 1995; 169 196-202
- 60 Siperstein A, Garland A, Engle K. et al . Local recurrence after laparoscopic radiofrequency thermal ablation of hepatic tumors. Ann Surg Oncol . 2000; 7 106-113
- 61 Topal B, Aerts R, Penninckx F. Laparoscopic radiofrequency ablation of unresectable liver malignancies: feasibility and clinical outcome. Surg Laparosc Endosc Percutan Tech . 2003; 13(1) 11-15
- 62
Wood T F, Rose D M, Chung M. et al .
Radiofrequency ablation of 231 unresectable hepatic tumors: indications, limitations,
and complications.
Ann Surg Oncol .
2000;
7
593-600
Reference Ris Wihthout Link
- 63 Goldberg S N, Hahn P F, Tanabe K K. et al . Percutaneous radiofrequency tissue ablation:does perfusion-mediated tissue cooling limit coagulation necrosis?. J Vasc Interv Radiol . 1998; 9 101-111
- 64 Curley S A, Davidson B S, Fleming R Y. et al . Laparoscopically guided bipolar radiofrequency ablation of areas of porcine liver. Surg Endosc . 1997; 11 729-733
- 65 Buscarini L, Buscarini E, Di Stasi M, Quaretti P, Zangrandi A. Percutaneous radiofrequency thermal ablation combined with transcatheter arterial embolization in the treatment of large hepatocellular carcinoma. Ultraschall Med . 1999; 20 47-53
- 66 Aschoff A J, Merkle E M, Wong V. et al . How does alteration of hepatic blood flow affect liver perfusion and radiofrequency-induced thermal lesion size in rabbit liver?. J Magn Reson Imaging . 2001; 13 57-63
- 67 De Baere T, Bessoud B, Dromain C. et al . Percutaneous radiofrequency ablation of hepatic tumors during temporary venous occlusion. AJR Am J Roentgenol . 2002; 178 53-59
- 68 Miao Y, Ni Y, Yu J, Zhang H, Baert A, Marchal G. An ex vivo study on radiofrequency tissue ablation: increased lesion size by using an “expandable-wet” electrode. Eur Radiol . 2001; 11 1841-1847
- 69 Giorgio A, Tarantino L, de Stefano G. et al . Percutaneous sonographically guided saline-enhanced radiofrequency ablation of hepatocellular carcinoma. AJR Am J Roentgenol . 2003; 181 479-484
- 70 Hansler J, Frieser M, Schaber S. et al . Radiofrequency ablation of hepatocellular carcinoma with a saline solution perfusion device: a pilot study. J Vasc Interv Radiol . 2003; 14 575-580
- 71 Kettenbach J, Kostler W, Rucklinger E. et al . Percutaneous saline-enhanced radiofrequency ablation of unresectable hepatic tumors: initial experience in 26 patients. AJR Am J Roentgenol . 2003; 180 1537-1545
- 72 Goldberg S N, Kamel I R, Kruskal J B. et al . Radiofrequency ablation of hepatic tumors: increased tumor destruction with adjuvant liposomal doxorubicin therapy. AJR Am J Roentgenol . 2002; 179 93-101
- 73 Kitamoto M, Imagawa M, Yamada H. et al . Radiofrequency ablation in the treatment of small hepatocellular carcinomas: Comparison of the radiofrequency effect with and without chemoembolization. AJR Am J Roentgenol . 2003; 181 997-1003
- 74 Goldberg S N, Kruskal J B, Oliver B S, Clouse M E, Gazelle G S. Percutaneous tumor ablation: increased coagulation by combining radiofrequency ablation and ethanol instillation in a rat breast tumor model. Radiology . 2000; 217 827-831
- 75 Solbiati L, Goldberg S N, Ierace T, Dellanoce M, Livraghi T, Gazelle G S. Radiofrequency ablation of hepatic metastases: Postprocedural assessment with a US microbubble contrast agaent- early experience. Radiology . 1999; 211 643-649
- 76 Wen Y L, Kudo M, Zheng R Q. et al . Radiofrequency ablation of hepatocellular carcinoma: Therapeutic response using contrast-enhanced coded phase-inversion harmonic sonography. AJR Am J Roentgenol . 2003; 181 57-63
- 77 Numata K, Isozaki T, Ozawa Y. et al . Percutaneous ablation therapy guided by contrast-enhanced sonography for patients with hepatocellular carcinoma. AJR Am J Roentgenol . 2003; 180 143-149
- 78 Cioni D, Lencioni R, Rossi S. et al . Radiofrequency thermal ablation of hepatocellular carcinoma: using contrast-enhanced harmonic power doppler sonography to assess treatment outcome. AJR Am J Roentgenol . 2001; 177 783-788
- 79 Meloni M F, Goldberg S N, Livraghi T. et al . Hepatocellular carcinoma treated with radiofrequency ablation: comparison of pulse inversion contrast-enhanced harmonic sonography, contrast-enhanced power Doppler sonography, and helical CT. AJR Am J Roentgenol . 2001; 177 375-380
- 80 Morimoto M, Sugimori K, Shirato K. et al . Treatment of hepatocellular carcinoma with radiofrequency ablation: radiologic-histologic correlation during follow-up periods. Hepotology . 2002; 35 1467-1475
- 81 Goldberg S N, Charboneau J W, Dodd G D. et al . Image-guided tumor ablation: proposal for stardardization of terms and reporting criteria. Radiology . 2003; 228 335-345
- 82 Boaz T L, Lewin J S, Chung Y C, Duerk J L. MR monitoring of MR-guided radiofrequency thermal ablation of normal liver in an animal model. J Magn Reson Imaging . 1998; 8 64-69
- 83 Steiner P, Botnar R, Goldberg S N, Gazelle G S, Debtin J F. Monitoring of radiofrequency tissue ablation in an interventional MR environment: preliminary ex vivo and in vivo results. Invest Radiol . 1997; 32 671-678
- 84 Anderson G S, Brinkmann F, Soulen M C, Alavi A, Zhuang H. FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation. Clin Nucl Med . 2003; 28 192-197
- 85 Livraghi T, Solbiati L, Meloni M F. et al . Treatment of focal liver tumors with percutaneous complications encountered in a multicenter study. Radiology . 2003; 226 441-451
- 86 Llovet J M, Vilana R, Bru C. et al . Increased risk of tumor seeding after Percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology . 2001; 33 1124-1129
- 87 De Sio I, Castellano L, De Girolamo V. et al . Tumor dissemination after radiofrequency ablation of hepatocellular carcinoma. Hepatology . 2001; 34 609-610
- 88 Livraghi T, Vettori C, Torzilli G. et al . Percutaneous ethanol injection of hepatic tumors single-session therapy under general anesthesia. AJR Am J Roentgenol . 1993; 160 1065-1069
- 89 Molmenti E P, Marsh J W, Dvorchik I. et al . Hepatobiliary malignancies: primary hepatic malignant neoplasms. Surg Clin North Am . 1999; 79 43-57
- 90 De Baere T, Risse O, Kuoch V. et al . Adverse events during radiofrequency treatment of 582 hepatic tumors. AJR Am J Roentgenol . 2003; 181 695-700
- 91 Chopra S, Dodd G D, Chanin M P, Chintapalli K N. Radiofrequency ablation of hepatic tumors adjacent to the gall bladder: feasibility and safety. AJR Am J Roentgenol . 2003; 180 697-701
- 92 Titton R L, Gryzenia P C, Gervais D A. et al . Continuous high-output drainage of hepatic abscess 3 months after radiofrequency ablation of hepatocellular carcinoma. AJR Am J Roentgenol . 2003; 180 1079-1084
- 93 Lu D S, Raman S S, Vodopich D J. et al . Effect on vessel size on creation of hepatic radiofrequency lesions in pigs: assessment of the “heat sink” effect. AJR Am J Roentgenol . 2002; 178 47-51
- 94 Shibata T, Limuro Y, Yamamoto Y. et al . Small hepatocellular carcinoma: comparison of radio-frequency ablation and percutaneous microwave coagulation therapy. Radiology . 2002; 223 331-337
- 95 Goldberg S N. Comparison of techniques of image-guided ablation of focal liver tumors. Radiology . 2002; 223 304-307