Pharmacomechanical thrombolysis (PMT) has emerged as an alternate treatment used in
most patients presenting with a thrombosed hemodialysis graft. Although the gold standard,
surgical revision of thrombosed hemodialysis grafts is reserved for those cases of
recurrent thrombosis despite the use of percutaneous techniques and for complicated
cases after PMT. Nevertheless, as for every other procedure, PMT has its own set of
limitations and cost issues. New mechanical devices have begun to emerge on the market
to help accelerate clot dissolution with or without thrombolytic medications. These
devices have decreased the time required to lyse clot and decrease the overall cost
of percutaneous treatment. This article describes the use of the Microtherapeutics,
Inc. (MTI) Castañeda over-the-wire brush and our experience with this device in the
treatment of the clotted hemodialysis graft.
KEYWORDS
Dialysis - thrombolysis - intervention
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Flavio CastañedaM.D.
University of Illinois College of Medicine at Peoria, Department of Radiology
1 Illini Drive, Box 1649
Peoria, IL 61656
Email: flavio@miit.com