Int J Sports Med 2007; 28(11): 916-920
DOI: 10.1055/s-2007-964983
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Ventilatory and Lactic Thresholds in Subjects with Sickle Cell Trait

L. Marlin1 , F. Sara1 , S. Antoine-Jonville1 , P. Connes1 , M. Etienne-Julan2 , O. Hue1
  • 1Department of Physiology, Laboratoire Actes UPRES‐EA 3596, Pointe-À-Pitre Cedex, Guadeloupe
  • 2Centre Caribéen de la Drépanocytose «Guy Mérault», Centre Hospitalier et Universitaire de Pointe-à-Pitre, Pointe-À-Pitre, Guadeloupe
Further Information

Publication History

accepted after revision September 21, 2006

Publication Date:
11 May 2007 (online)

Abstract

This study investigated 1) whether ventilatory and lactic thresholds (VT and LT, respectively) are different in sickle cell trait carriers (SCTc) and subjects with normal hemoglobin (control group), and 2) whether the first LT and VT and the second LT and VT are respectively coincident in the two populations. Seven SCTc and 8 control subjects performed an incremental exercise test (IET). Blood lactate concentration and cardioventilatory variables were analyzed at rest and during IET. No significant difference in the ventilatory parameters (notably, maximal oxygen uptake [V·O2max] and the ventilatory thresholds) or the lactic thresholds was observed between the two groups. In both SCTc and control subjects, the LTs and VTs did not occur at the same exercise intensity. The first VT did not coincide with the first LT, in contrast with the second VT and the second LT, which coincided in both groups. In conclusion, SCTc exhibited normal ventilatory and lactic responses during a progressive and maximal exercise test assessing aerobic physical fitness.

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 Mr.
Laurent Marlin

Department of Physiology
Laboratoire ACTES UPRES‐EA 3596
UFR STAPS Campus de Fouillole

Université des Antilles et de la Guyane BP 592

97159 Pointe-à-Pitre Cedex

Guadeloupe

Phone: + 33 590 48 92 27

Fax: + 33 590 48 92 79

Email: laurentmarlin@hotmail.com

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