Solitary fibrous tumors (SFTs) are unusual mesenchymal tumors that were first described
as primary spindle-cell neoplasms of the pleura. These tumors have been described
in many other locations, including the urogenital system, orbit, mediastinum, and
upper respiratory tract. Twenty-two cases of an SFT of the paranasal sinuses and nasal
cavity have been reported, but none described a malignant SFT extending through the
anterior skull base. A 70-year-old man had a 6-month history of unilateral left-sided
epiphora and nasal obstruction. Computed tomography and magnetic resonance imaging
showed a large left-sided nasal cavity mass with extension into the left extraconal
orbit and intracranial extension through the left cribriform plate and ethmoid roof.
The patient underwent preoperative embolization of the internal maxillary artery and
a subsequent anterior craniofacial resection via a midfacial degloving approach and
a left anterior craniotomy. Histopathological analysis of the specimen was consistent
with a malignant SFT.
Solitary fibrous tumor - midfacial degloving - anterior skull base - nasal cavity
- immunohistochemistry
