Frauenheilkunde up2date 2008; 2(1): 3-8
DOI: 10.1055/s-2008-1004612
Forum

© Georg Thieme Verlag KG Stuttgart · New York

Osteoporose in der gynäkologischen Sprechstunde

U. Schröder, H. Siggelkow
Further Information

Publication History

Publication Date:
13 February 2008 (online)

Einführung

Osteoporose und Gynäkologie - wo liegen die Schnittstellen? Die frauenärztliche Betreuung bietet die kontinuierliche Anbindung vom Kindesalter bis ins fortgeschrittene Senium, von der Verordnung der ersten Pille über die Betreuung der Frau in der Schwangerschaft, der Verordnung von Hormonen in den Wechseljahren bis zur Therapie beim Mammakarzinom. Jeder dieser Punkte zeigt einen definierten Bezug zur Knochengesundheit - und im Rahmen der Betreuung stellt sich die Frage, ob und inwieweit eine Osteoporose entsteht oder verhindert werden kann.

Literatur

  • 1 Felsenberg D et al. Prevalence of vertebral spinal deformities in women and men in Germany. EVOS group in Germany.  Med Klin. 1998;  93 31-34
  • 2 WHO . Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group.  World Health Organ Tech Rep Ser. 1994;  843
  • 3 Cooper C et al. Population-based study of survival after osteoporotic fractures.  Am J Epidemiol. 1993;  137 1001-1005
  • 4 Pfeilschifter J. 2006 DVO-guideline for prevention, diagnosis, and therapy of osteoporosis for women after menopause, for men after age 60 executive summary guidelines.  Exp Clin Endocrinol Diabetes. 2006;  114 611-622
  • 5 Podsiadlo D, Richardson S. The timed “Up & Go”: a test of basic functional mobility for frail elderly persons.  J Am Geriatr Soc. 1991;  39 142-148
  • 6 Guralnik J M et al. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability.  N Engl J Med. 1995;  332 556-561
  • 7 Gluer C C et al. Association of five quantitative ultrasound devices and bone densitometry with osteoporotic vertebral fractures in a population-based sample: the OPUS Study.  J Bone Miner Res. 2004;  19 782-793
  • 8 Schott A M et al. Should age influence the choice of quantitative bone assessment technique in elderly women? The EPIDOS study.  Osteoporos Int. 2004;  15 196-203
  • 9 Tsai K S et al. Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis.  J Clin Invest. 1984;  73 1668-1672
  • 10 Bischoff-Ferrari H A et al. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes.  Am J Clin Nutr. 2006;  84 18-28
  • 11 Siggelkow H. Vitamin D and old age.  MMW Fortschr Med. 2007;  149 36-37
  • 12 Eastell R. Aromatase inhibitors and bone.  J Steroid Biochem Mol Biol. 2007;  106 157-161
  • 13 Mincey B A et al. Risk of cancer treatment-associated bone loss and fractures among women with breast cancer receiving aromatase inhibitors.  Clin Breast Cancer. 2006;  7 127-132
  • 14 Hillner B E et al. American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer.  J Clin Oncol. 2003;  21 4042-4057
  • 15 Aapro M et al. Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel.  Ann Oncol. 2007; 
  • 16 Winer E P et al. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004.  J Clin Oncol. 2005;  23 619-629
  • 17 Wisser J et al. Changes in bone density and metabolism in pregnancy.  Acta Obstet Gynecol Scand. 2005;  84 349-354
  • 18 Lanham S A et al. Intrauterine programming of bone. Part 1: Alteration of the osteogenic environment.  Osteoporos Int. 2007; 
  • 19 Lanham S A et al. Intrauterine programming of bone. Part 2: Alteration of skeletal structure.  Osteoporos Int. 2007; 
  • 20 Kovacs C S. Calcium and bone metabolism during pregnancy and lactation.  J Mammary Gland Biol Neoplasia. 2005;  10 105-118
  • 21 Hellmeyer L et al. The use of i. v. bisphosphonate in pregnancy-associated osteoporosis: case study.  Exp Clin Endocrinol Diabetes. 2007;  115 139-142
  • 22 Steib-Furno S et al. Pregnancy-related hip diseases: incidence and diagnoses.  Joint Bone Spine. 2007;  74 373-378
  • 23 O'Sullivan S M et al. Bisphosphonates in pregnancy and lactation-associated osteoporosis.  Osteoporos Int. 2006;  17 1008-1012

Priv. Doz. Dr. med. H. Siggelkow

Fachärztin für Innere Medizin · Endokrinologie und Diabetologie (DDG) · Osteologin DVO · Endokrinologikum Göttingen

Von-Siebold-Str. 3

37075 Göttingen

Email: heide.siggelkow@endokrinologikum.com


Universität Göttingen · Bereich Humanmedizin · Abt. für Gastroenterologie und Endokrinologie

Robert-Koch-Str. 40

37075 Göttingen

Email: hsiggel@med.uni-goettingen.de

    >