ABSTRACT
Neuropathic disorders encompass those that affect the neuron's cell body or neuronopathies,
those affecting the peripheral process, or peripheral neuropathies. The peripheral
neuropathies can be broadly subdivided into the myelinopathies and axonopathies. These
conditions can be hereditary or acquired. Each of these disorders has distinct clinical
features that enable neurologists to recognize the various patterns of presentation.
Once a particular pattern is established, further laboratory studies including electrophysiologic
testing, nerve biopsy, and blood and cerebrospinal fluid examination can be performed
to confirm the clinical impression. Therapy is available in some to correct the underlying
disease state or at least to improve symptoms.
Keywords
peripheral neuropathy - neuronopathy - motor neuron disease - gan-glionopathy - myelinopathy
- axonopathy
