Protein S gene polymorphisms Pro626 and nt2698 – no correlation to free protein S levels or protein S activities

• References

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• 3 Boerger LM, Morris PC, Thurnau GR. et al Oral Contraceptives and Gender Affect Protein S Status. Blood 1987; 69: 692-4.
• 4 Leroy-Matheron C, Duchemin J, Levent M. et al Genetic Modulation of Plasma Protein S Levels by Two Frequent Dimorphisms in the PROS1 Gene. Thromb Haemost 1999; 82: 1088-92.
• 5 Leroy-Matheron C, Duchemin J, Levent M. et al Influence of the nt 2148 A to G Substitution (Pro626 Dimorphism) in the PROS1 Gene on Circulating Free Protein S Levels in Healthy Volunteers – Reappraisal of Protein S Normal Ranges. Thromb Haemost 2000; 83: 798-9.
• 6 EU directive 2002/98/EC.
• 7 The Council of Europe Guide to preparation and quality assurance of blood components 11 th edition.
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