A novel mutation of antithrombin deficiency in six family siblings and the clinical combat

Thromb Haemost 2015; 114(04): 859-861
DOI: 10.1160/TH15-01-0040

Letters to the Editor

Schattauer GmbH

Yona Nadir

¹Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel

,

Ron Hoffman

¹Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel

,

Javier Corral

²Centro Regional de Hemodonación, C/ Ronda de Garay s/n, Murcia, Spain

,

Yaron Barak

³Department of Cardiac Surgery, Rambam Health Care Campus, Haifa, Israel

,

Tal Hasin

⁴Department of Cardiology, Rambam Health Care Campus, Haifa, Israel

,

Anat Keren-Politansky

¹Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel

,

Benjamin Brenner

¹Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel

References
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2 Calcaterra D, Martin JT, Ferneini AM. et al. Acute mesenteric and aortic thrombosis associated with antithrombin deficiency: a rare occurrence. Ann Vasc Surg 2010; 24: 415e5-7.
3 Tu CM, Hsueg CH, Chu KM. et al. Simultaneous thromboses of double coronary arteries in a young male with antithrombin III deficiency. Am J Emerg Med 2009; 27: 1169e3-6.
4 Roldan V, Ordonez A, Marin F. et al. Antithrombin Cambridge II (A384S) supports a role for anti-thrombin deficiency in arterial thrombosis. Thromb Haemost 2009; 101: 483-486.
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6 Zeng W, Tang L, Jian XR. et al. Genetic analysis should be included in clinical practice when screening for antithrombin deficiency. Thromb Haemost 2015; 113: 262-271.