Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria

Niamh O’Regan; Chris Moxon; Kristina Gegenbauer; Jamie M. O’Sullivan; Alain Chion; Owen P. Smith; Roger J. S. Preston; Teresa M. Brophy; Alister G. Craig; James S. O’Donnell

doi:10.1160/TH15-10-0796

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2016; 115(04): 773-780
DOI: 10.1160/TH15-10-0796

Blood Cells, Inflammation and Infection

Schattauer GmbH

Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria

Niamh O’Regan^*

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

,

Chris Moxon^*

²Institute of Infection and Global Health, University of Liverpool, UK

³Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi

,

Kristina Gegenbauer

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

,

Jamie M. O’Sullivan

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

,

Alain Chion

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

,

Owen P. Smith

⁴National Children’s Research Centre, Our Lady’s Children’s Hospital, Crumlin, Dublin, Ireland

⁵Haematology Dept, Our Lady’s Children’s Hospital, Dublin, Ireland

,

Roger J. S. Preston

⁵Haematology Dept, Our Lady’s Children’s Hospital, Dublin, Ireland

⁶Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Ireland

,

Teresa M. Brophy

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

,

Alister G. Craig

⁷Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK

,

James S. O’Donnell

¹Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity College Dublin, Ireland

⁸National Centre for Hereditary Coagulation Disorders, St James’s Hospital, Dublin, Ireland

› Author Affiliations

Abstract

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Keywords

Osteoprotegerin - von Willebrand factor - cerebral malaria - Plasmodium falciparum - Plasmodium berghei

References

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