Download PDF
Vet Comp Orthop Traumatol 2014; 27(05): 395-397
DOI: 10.3415/VCOT-13-11-0140
Brief Communication
Schattauer GmbH

Combined prevalence of inherited skeletal disorders in dog breeds in Belgium

F. Coopman
1   Holbigenetics NV, Waarschoot, Belgium
3   Department of Applied Biosciences, Faculty of Biosciences Engineering, Ghent University, Ghent, Belgium
4   Department of Medical Imaging and Orthopedics, Ghent University, Merelbeke, Belgium
,
B. Broeckx
2   Laboratory for Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium
,
E. Verelst
3   Department of Applied Biosciences, Faculty of Biosciences Engineering, Ghent University, Ghent, Belgium
,
D. Deforce
2   Laboratory for Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium
,
J. Saunders
4   Department of Medical Imaging and Orthopedics, Ghent University, Merelbeke, Belgium
,
L. Duchateau
5   Department of Physiology and Biometrics, Ghent University, Merelbeke, Belgium
,
G. Verhoeven
4   Department of Medical Imaging and Orthopedics, Ghent University, Merelbeke, Belgium
› Author Affiliations
Further Information

Publication History

Received: 20 November 2013

Accepted: 11 June 2014

Publication Date:
22 December 2017 (online)

    Permissions and Reprints

Summary

Canine hip dysplasia (CHD), canine elbow dysplasia (CED), and humeral head osteochondrosis (HHOC) are inherited traits with uneven incidence in dog breeds. Knowledge of the combined prevalence of these three disorders is necessary to estimate the effect of the currently applied breeding strategies, in order to improve the genetic health of the population. Official screening results of the Belgian National Committee for Inherited Skeletal Disorders (NCSID) revealed that an average of 31.8% (CHD, CED, or both; n = 1273 dogs) and 47.2% (CHD, CED, HHOC, or a combination of these three diseases; n = 250 dogs) of dogs are mildly to severely affected by at least one skeletal disorder. According to the current breeding recommendations in some dog breeds in Belgium, these animals should be restricted (mild signs) or excluded (moderate to severe signs) from breeding. The introduction of genetic parameters, such as estimated breeding values, might create a better approach to gradually reduce the incidence of these complex inherited joint disorders, without compromising genetic population health.

Keywords

Canine hip dysplasia - canine elbow dysplasia - osteochondrosis - combined prevalence - Belgium
 

  • References

  • 1 Coopman F, Verhoeven G, Saunders J. et al Prevalence of hip dysplasia, elbow dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Vet Rec 2008; 163: 654-658.
    CrossrefPubMedGoogle Scholar
  • 2 Morgan JP, Wind A, Davidson AP. Bone dysplasias in the Labrador Retriever: A Radiographic Study. JAAHA 1999; 35: 1-9.
    PubMedGoogle Scholar
  • 3 Lewis TW, Blott SC, Woolliams JA. Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds. BMC Genet 2013; 14: 16.
    PubMedGoogle Scholar
  • 4 Hou Y, Wang Y, Lu X. et al Monitoring hip and elbow dysplasia achieved modest genetic improvement of 74 dog breeds over 40 years in USA. PLoS One 2013; 8: e76390
    CrossrefPubMedGoogle Scholar
  • 5 Hartmann P, Stock KF, Distl O. Multivariate prediction of breeding values for canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese Mountain dog. Berl Munch Tierarztl Wochenschr 2012; 125: 432-440.
    PubMedGoogle Scholar
  • 6 Cachon T, Genevois JP, Remy D. et al Risk of simultaneous phenotypic expression of hip and elbow dysplasia in dogs: A study of 1,411 radiographic examinations sent for official scoring. Vet Comp Orthop Traumatol 2010; 23: 28-30.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 7 Broeckx BJ, Verhoeven G, Coopman F. et al. The effect of positioning, reason for screening and the referring veterinarian on prevalence estimates of canine hip dysplasia. Vet J 2014 May 22; [Epub ahead of print]
    PubMedGoogle Scholar
  • 8 Janutta V, Hamann H, Klein S. et al Genetic evaluation of elbow angles as predictors of elbow dysplasia in German Shepherd dogs. J Vet Med A Physiol Pathol Clin Med 2005; 52: 254-261.
    CrossrefPubMedGoogle Scholar
  • 9 Necas A, Dvorak M, Zatloukal J. Incidence of osteochondrosis in dogs and its late diagnosis. Acta Vet Brno 1999; 68: 131-139.
    CrossrefPubMedGoogle Scholar
  • 10 Dziuk E. The OFA and the role of canine health databases [Article on Website]. Orthopedic Foundation for Animals 2010 Available from http://www.offa.org/dbaserole.html CHD and CED database: consulted on 2014-01-30
    PubMedGoogle Scholar