Pharmacopsychiatry

Issue 04 · July 1986

Recommend Journal

Editorial
127
Delini-Stula, A.:
14th AGNP Meeting, Nürnberg 1985

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Schizophrenia and Antipsychotic Drugs Introductory Papers
128
Heimann, H.:
Models of Experience and Behavior in Psychotic Disorders

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134
Delini-Stula, A.:
Neuroanatomical, Neuropharmacological and Neurobiochemical Target Systems for Antipsychotic Activity of Neuroleptics

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145
Langer, G.; Ackenheil, M.; Dixon, A. K.; Kurtz-May, G.; Möller, H. J.; Müller-Spahn, F.; Pietzcker, A.; Saletu, B.; Schönbeck, G.:
The Psychopharmacology and Neuroendocrinology of Neuroleptics: The State of the Art from a Clinical Perspective

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149
Christensen, A. V.; Greil, W.; Haag, H.; Havemann, U.; Kehr, W.; Kuschinsky, K.; Porsolt, R. D.; Rüther, E.; Tegeler, J.:
Animal Models for Assessing Extrapyramidal-Motor Side-Effects of Neuroleptics

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156
Möller, H. J.:
Methodological Problems of Long-term Studies in Psychopharmacology

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161
Pietzcker, A.; Gaebel, W.; Köpcke, W.; Linden, M.; Müller, P.; Müller-Spahn, F.; Schüssler, G.; Tegeler, J.:
A German Multicenter Study on the Neuroleptic Long-term Therapy of Schizophrenic Patients

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167
Greil, W.; Haag, M.; Huber, D.; Schmidt, St.:
Maintenance Treatment in Affective Disorders: Overview and Design of a Collaborative Study

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172
Fuhr, P.; von Luckner, N.; Woggon, B.:
Can Pretreatment Data Predict Withdrawals in Clinical Trials of Psychotropic Drugs?

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174
Woggon, B.; Biber, M.; Stassen, H. H.:
Clinical Trials of Antidepressants: Have the Patient Samples Changed During the Years?

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176
Bender, W.; Haag, M.; Haag, H.; Greil, W.; Engel, R.:
Compliance in Psychiatry: Development of a Patient Questionnaire

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178
Maier, W.; Philipp, M.; Schlegel, S.; Heuser, I.; Buller, R.; Frommberger, U.; Wetzel, H.; Wilhelmi, D.; Wittenborg, A.; Demuth, W.:
Operational Diagnoses for Schizophrenic and Schizoaffective Disorders

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180
Philipp, M.; Maier, W.; Frommberger, U.; Wilhelmi, D.; Wetzel, H.; Schlegel, S.; Buller, R.; Heuser, I.; Demuth, W.; Wittenborg, A.:
Operational Diagnoses for Schizophrenic and Schizoaffective Disorders

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182
Heuser, J.; Maier, W.:
Depression, Melancholia, and Memory Recognition:
A Signal Detection Analysis

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184
Schlegel, S.; Kretzschmar, K.:
Computerized Tomographic Findings in Affective Disorder

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186
Kohnen, R.; Krüger, H. P.:
Drug Effects on Human Social Behavior:
Changes in Talking Activities Induced by CGP 361/A, a Beta-blocking Agent

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188
Gaebel, W.; Ulrich, G.:
Visuomotor Performance of Schizophrenic Patients and Normal Controls - I. Results of a Visual Fixation Task

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190
Gaebel, W.; Ulrich, G.:
Visuomotor Performance of Schizophrenic Patients and Normal Controls - II. Results of a Visual Search Task

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192
Giedke, H.:
Hibernation as a Model of Endogenous Depression

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194
Filser, J. G.; Spira, F. J.; Gabel, A.; Beckmann, H.; Müller, W. E.:
Comparative Determination of 3-Methoxy-4-Hydroxyphenylglycol and its Conjugated Derivatives in the Urine of Depressed Patients and Healthy Controls

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196
Bohl, J.; Störkel, St.; Schulze, E.; Tschank, G.; Haas, St.; Krausbeck, E.; Gather, W.; Katzman, K.; Brocks, D.:
Alzheimer's Disease: A Cerebral Amyloidosis
A Cooperative Study to Correlate Clinical, Biochemical and Pathologic-anatomical Findings

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200
Ziegler, G.; Ludwig, L.; Fritz, G.:
Effect of the Specific Benzodiazepine Antagonist Ro 15-1788 on Sleep

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202
Renfordt, E.; Ulrich, G.:
Relations among Psychopathology, Nonverbal Behavior (Speech Activity), and Neurophysiology (Topography of Alpha Power) under Antidepressive Drug Treatment

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206
Dreher, A.; Baer-Degitz, M.; Köchert, R.; Nagel, L.; Salzer, W.-W.:
Clinical Study of the Correlation Between the Antipsychotic Operative Dose of Perphenazine and Fine Motor Extrapyramidal Inhibition in Haase's Handwriting Test

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210
Klieser, E.; Felgenträger, H. J.:
Fluperlapine: A Therapeutic Alternative in Schizophrenic Psychoses

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212
König, W.; Kunow, J.; Kniehl, R.; Reimer, F.:
Neuroleptics in the Treatment of Schizophrenia: Have there been Changes in the Dosage Regimen?

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214
Gutzmann, H.; Gaebel, W.; Linden, M.:
One Year Follow-up of Schizophrenic Patients in Private Psychiatric Practice

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216
Ruhland, M.; Fuchs, A. M.:
Lack of Antagonism by Ro 15-1788 on Timelotem (KC 7507) - a Benzodiazepine with Antipsychotic and Anxiolytic Properties

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218
Ruhland, M.; Tulp, M.; Muesch, H. R.; Fuchs, A. M.:
Timelotem - an Antipsychotic Benzodiazepine Derivative

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220
Ulrich, G.; Müller-Oerlinghausen, B.; Gaebel, W.:
Changes in the Topographical Distribution of Absolute Alpha-power in the Resting EEG of Schizophrenic In-patients under Neuroleptic Medication

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222
Gaebel, W.; Ulrich, G.:
Topographical Distribution of Absolute Alpha-power in Schizophrenic Outpatients - On-drug Responders vs. Nonresponders

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224
Wildenauer, D. B.; Bondy, B.; Welter, D.; Ackenheil, M.:
The Phospholipid Composition of Lymphocytes in Schizophrenic Patients: Effect of Treatment with Neuroleptics

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228
Naber, D.; Albus, M.; Bürke, H.; Müller-Spahn, F.; Münch, U.; Reinertshofer, T.; Wissmann, J.; Ackenheil, M.:
Neuroleptic Withdrawal in Chronic Schizophrenia.
CT and Endocrine Variables are not Valid Predictors of Psychopathological Changes

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230
Schreiber, W.; Kissling, W.; Möller, H. J.; Bäuml, J.; Gain, T.; Bottermann, P.:
TRH-Test and Psychiatric Disorders

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232
Mühlbauer, H. D.; Müller-Oerlinghausen, B.:
Fenfluramine Stimulation of Morning Cortisol in Manic-depressive Patients and Lithium Prophylaxis: A Marker of (Auto-) Aggressiveness and Prophylactic Response?

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233
Roncoroni, D.:
Prolactin as an Index of Neuroleptic Effects on the Neuroendocrine Regulatory Activity of the Hypotalamic Pituitary System

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235
Laakmann, G.; Neuhauser, H.; Hinz, A.; Neulinger, E.; Wittmann, M.:
Stimulation of Growth Hormone, Prolactin, and Cortisol by GHRH and DMI in Depressed Patients

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237
Laakmann, G.; Hinz, A.; Munz, T.; Schoen, H.-W.; Wittmann, M.; Zygan, K.:
Interactions of Alpha-2/Beta Receptors and DMI-lnduced GH, PRL and Cortisol Stimulation

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239
Laakmann, G.; Hinz, A.; Neulinger, E.; Strauss, A.; Wittmann, M.:
DMI-Induced Growth Hormone Stimulation in Healthy Subjects and Depressed Patients

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241
Mühlbauer, H. D.; Ziolko, H. U.:
Abnormalities of Anterior Pituitary Responsiveness to Hypothalamic Hormones in Bulimia

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245
Delini-Stula, A.; Hunn, Ch.:
Effects of Imipramine and Brofaromine, a Selective and Reversible MAO-A Inhibitor, on Novelty-oriented Behaviour in Rats

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247
Kapfhammer, H. P.; Hoff, P.; Golling, H.; Rüther, E.; Schmauss, M.:
Cimoxatone and Moclobemide, Two New MAO-lnhibitors, in the Treatment of Major Depressive Disorder

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249
Hoff, P.; Golling, H.; Kapfhammer, H. P.; Lund, R.; Pakesch, G.; Rüther, E.; Schmauss, M.:
Cimoxaton and Moclobemid, Two New MAO-lnhibitors:
Influence on Sleep Parameters in Patients with Major Depressive Disorder

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251
Schmauss, M.; Kapfhammer, H. P.; Meyr, P.; Hoff, P.:
Combined MAO-inhibitor and Tri-(Tetra) Cyclic Antidepressant Treatment in Therapy Resistant Depression

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253
Wendt, G.; Binz, U.; Fischer, E.:
Long-term Treatment with Oxaprotiline in Patients with Endogenous Depression

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255
Linden, M.; Schüssler, G.:
Compliance and Treatment Outcome of Antidepressant Therapy in Private Psychiatric Practice

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257
Boll, E.; Tarighati, M. A.; Holsboer, F.:
Clinical Application of Antidepressant-Plasma Level Analysis with High Pressure Liquid Chromatography (HPCL)

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259
Giedke, H.; Axmann, D.; Gaertner, H. J.; Rein, W.; Rötzer-Zimmer, F. T.:
Psychophysiological Predictors of Antidepressant Therapy Response?

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262
Philipp, M.; Beck, V.; Scherhag, R.; Glocke, M.; Schmidt, R.:
Biological and Psychopathological Prediction of Response to Doxepine in Depressive Outpatients

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264
Schmauss, M.; Laakmann, G.; Dieterle, D.:
Yohimbine in Combination with Tricyclic Antidepressants in the Treatment of Therapy-Resistant Depressed Patients

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266
Schmauss, M.; Laakmann, G.; Dieterle, D.:
Influence of Nomifensine on Prolactin Secretion in Depressed Inpatients

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268
Süss, St.; Boll, E.; Holsboer, F.:
Urinary Multisteroid Analysis Applying Glass-capillary Gas-chromatography - A New Technique to Assess Adrenocortical Activity in Depression

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270
Ulrich, G.; Renfordt, E.; Frick, K.:
Electroencephalographic Dynamics of Vigilance and Drug-response in Endogenous Depression.
A Comparison of Patients Treated with Amitriptyline or Pirlindole

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272
Ulrich, G.; Renfordt, E.; Frick, K.:
The Topographical Distribution of Alpha-activity in the Resting EEG of Endogenous-depressive In-patients with and without Clinical Response to Pharmacotherapy

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276
Calker, D. van; Greil, W.:
Effects of Lithium Ions on the Metabolism of Phosphoinositides: Studies with Rat Pheochromocytoma Cells (PC-12 cells)

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278
Haag, M.; Heidorn, A.; Haag, H.; Greil, W.:
Response to Stabilising Lithium Therapy and Sequence of Affective Polarity

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280
Möller, H. J.; Kissling, W.; Tavan, S.; Winter, I.:
Is Carbamazepine Able to Increase the Antimanic Effect of Haloperidol?

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282
Cabrera, J. F.; Mühlbauer, H. D.; Schley, J.; Stoll, K. D.; Müller-Oerlinghausen, B.:
Long-term randomized Clinical Trial on Oxcarbazepine vs Lithium in Bipolar and Schizoaffective Disorders: Preliminary Results.

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284
Müller-Oerlinghausen, B.; Imiela, M.:
In-vitro and In-vivo Studies on the Pharmacokinetics and Clinical Efficacy of Lithium Aspartate as Compared to Conventional Lithium Preparations

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286
Volk, J.; Müller-Oerlinghausen, B.:
Time Course of AMP-Documented Side-effects in Patients under Long-term Lithium Treatment

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290
Wastl, R.; Grohmann, R.; Rüther, E.:
Frequency of Increased Serum Liver-enzyme Levels under Treatment with Neuroleptics

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292
Dirschedl, P.; Grohmann, R.; Schmidt, L. G.:
Reliability of Adverse Drug Reaction Assessment

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294
Spieß-Kiefer, C.; Grohmann, R.; Rennig, E.; Rüther, E.; Scherer, J.; Schmidt, L. G.:
Acute Delirious Syndromes due to Psychotropic Drugs

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296
Wolf, B.; Rüther, E.; Brenner, P.-M.; Poser, W.; Schmidt, L. G.:
Abuse of and Dependence on Stimulants and Anorexigenic Drugs in Psychiatric Inpatients

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298
Bürke, H.; Grohmann, R.; Rüther, E.:
Psychiatric Outpatient Treatment: Developing Methods of Drug Surveillance

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300
Grohmann, R.; Dirschedl, P.; Rennig, E.; Scherer, J.; Schmidt, L. G.:
Methodological Problems in Assessment of Adverse Drug Reactions with Drug Combinations

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304
Bischoff, S.; Bruinink, A.; Krauss, J.; Schaub, M.; Vassout, A.:
In Vivo and in Vitro Characterization of Dopamine Receptors in Hippocampus and their Pharmacological Relevance

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306
Bischoff, S.; Vassout, A.; Delini-Stula, A.; Waldmeier, P.:
Interactions of Cipazoxapine, Citatepine, Eresepine, and Maroxepine with Central Dopamine (DA) Receptors: Effects on in Vivo (³H)Spiperone Binding, DA Metabolism, and Behavioral Parameters

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308
Fuchs, V.; Coper, H.:
Kinetic Characteristics of Some Neuronal Receptors After Combined Treatment with Diazepam and Haloperidol

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310
Heil, Th.; Jänicke, B.:
The Influence of P-Hydroxy-norephedrine on "Drug-taking-behavior" to D-Amphetamine

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312
Jänicke, B.; Schulze, G.:
Capacity of Thermoregulation in Different Aged Rats: Age as a Factor Modifying Thermoregulation

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314
Müller, W. E.; Groh, B.; Bub, O.; Hofmann, H. P.; Kreiskott, H.:
In vitro and In vivo Studies of the Mechanism of Action of Arfendazam, a novel 1,5-Benzodiazepine

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316
Waldmeier, P. C.; Bischoff, S.; Bittiger, H.; Hauser, K.; Vassout, A.; Delini-Stula, A.; Haeusler, A.; Schenkel, L.; Storni, A.:
Pharmacological Profiles of Four New Tetracyclic Dopamine Antagonists, Maroxepine, Citatepine, Eresepine, and Cipazoxapine

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318
Waldmeier, P. C.; Baumann, P. A.:
Ifoxetine: An Unusual 5-HT Uptake Inhibitor or an Inhibitor of 5-HT Release?

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322
Spiegel, R.; Berger, M.:
Workshop on Pharmacological and Clinical Studies with Cholinergic Drugs in Humans

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323
Azcona, A.; Roth, S.; Spiegel, R.:
Effects of the Muscarinic Agonist RS 86 in Healthy Volunteers

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326
Berger, M.; Krieg, J. C.; Rummler, R.; Raptis, C.; Morinigo, A.; Dose, M.; Benker, B.:
The Treatment of Mania with the Cholinomimetic Drug RS 86

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328
Tegeler, J.:
Cholinergic Drugs for the Treatment of Tardive Dyskinesia

Full Text PDF (175 kb)
333
Kallus, K. W.:
Agglutination of Single-case Data: Application to Individual Data in Experimental Designs

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337
Frank, D. R.:
Psychological Theories of the Effects of Placebos with Special Consideration for the Attribution Theory

Full Text PDF (151 kb)
339
Herz, A.:
The Role of Opioid Peptides in Placebo-induced Effects

Full Text PDF (99 kb)
341
Maier, W.; Buller, R.; Philipp, M.; Frommberger, U.:
Placebo-Controlled Long-Term Studies in Chronic Depressed Patients: Evaluation by Single-Case-Analyses

Full Text PDF (116 kb)
343
Laakmann, G.; Blaschke, D.:
Use of Placebo in Clinical Trials on Therapeutic Efficacy of Newly Developed Drugs in Outpatients

Full Text PDF (141 kb)
345
Janke, W.:
Consistency of Response to Placebo with Different Instructions

Full Text PDF (107 kb)
347
Saupe, R.:
The Use of Placebo as Seen by Nursing Staff

Full Text PDF (115 kb)
Discusion groups
140
Bischoff, S.; Bürki, H. R.; Emrich, H. M.; Jaeckel, J.; Kornhuber, J.; Ruhland, M.; Schmid, W. J.; Woggon, B.:
Biochemical and Molecular Mechanisms of Action of Neuroleptics, Alternatives to the Classical Dopamine Hypothesis: Minutes of the Discussion Group

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Methodological Problems in Planning, Performing and Analysing of Long-Term Studies with psychotropic Drugs
152
Schou, M.:
Methodological Problems of Prophylactic Trials in Recurrent Affective Illness
A Historical Perspective

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Methodology of Clinical Trials
170
Haug, H.-J.; Fähndrich, E.:
Problems in Defining Response in Therapy Studies

Full Text PDF (104 kb)
Pharmaco-EEG, Sleep,Neuropsychophysiology
198
Wiegand, M.; Berger, M.; Zulley, J.; von Zerssen, D.:
The Effect of Trimipramine on Sleep in Patients with Major Depressive Disorder

Full Text PDF (147 kb)
Antipsychotic Drugs and Extrapyramidal Side-Effects
204
Woggon, B.; Beckmann, H.; Heinrich, K.; Linden, M.; Krebs, E.; Küfferle, B.; Pflug, B.; Rüther, E.; Schied, H. W.:
Clinically Relevant Differences in the Therapeutic Profile of Fluperlapine Compared to Haloperidol in the Treatment of Schizophrenic Psychosis - Results of a Multicentre Double-blind Study

Full Text PDF (128 kb)
Antipsychotic Drugs:Clinical Studies and Psychophysiology
208
Gaebel, W.; Pietzcker, A.; Baumgartner, A.:
3-Year Follow-up of Schizophrenic Patients - Outcome Dimensions and Neuroleptic Treatment

Full Text PDF (115 kb)
Immunology and Neuroendocrinology in Psychic Disorders
226
Moises, H. W.; Beck, J.; Schindler, L.; Kirchner, H.:
Decreased Interferon Production in Schizophrenic Patients

Full Text PDF (117 kb)
Antidepressant Drugs
243
Oefele, K. v; Grohmann, R.; Rüther, E.:
Adverse Drug Reactions in Combined Tricyclic and MAOI Therapy

Full Text PDF (140 kb)
Lithium
274
Hegerl, U.; Ulrich, G.; Müller-Oerlinghausen, B.:
Augmenting - Reducing Response to Auditory Evoked Potentials and its Relationship to the Prophylactic Effect of Lithium Salts

Full Text PDF (137 kb)
Adverse Drug Reactions(The AMüP Study Group)
288
Schmidt, L. G.; Grohmann, R.; Müller-Oerlinghausen, B.; Ochsenfahrt, H.:
Tolerability and Safety of Antidepressant Drugs in Psychiatric In- and Out-patients Assessed by two Drug Surveillance Systems

Full Text PDF (161 kb)
Experimental Pharmacology
302
Bering, B.; Spira, F.; Schanz, H.; Gattaz, W. F.; Müller, W. E.:
Do Human Erythrocyte Membranes Contain Muscarinic Cholinergic Receptors?

Full Text PDF (137 kb)
Drug Epidemiology
320
Koenig, W.; Rüther, E.; Filipiak, B.; Keil, U.:
Determinants of Psychotropic Drug Intake in a Metropolitan Population

Full Text PDF (142 kb)
Workshop on One Case Experiments in Pharmacopsychiatry - Possibilities and Limitations
331
Wolf, G. K.:
Basic Questions for the Use of Single Case Statistics

Full Text PDF (109 kb)
Workshop on New Aspects of the Placebo Problem
335
Netter, P.; Heck, S.; Müller, H. J.:
What Selection of Patients is Achieved by Requesting Informed Consent in Placebo Controlled Drug Trials?

Full Text PDF (138 kb)

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