DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue 03 · Volume 28 · 2002 DOI: 10.1055/s-002-2043 Recombinant Factor VIII Products and Hemophilia A: Efficacy, Safety, and Inhibitor Development Editor in Chief Eberhard F. Mammen M.D.,, Guest Editor Jan J. Michiels M.D. Ph.D.

C-1
Continuing Medical Education
241
Lee, Christine: The Use of Recombinant Factor VIII Products in Previously Treated Patients with Hemophilia A: Pharmacokinetics, Efficacy, Safety, and Inhibitor Development
247
Barrowcliffe, Trevor W.; Raut, Sanjeev; Sands, Dawn; Hubbard, Anthony R.: Coagulation and Chromogenic Assays of Factor VIII Activity: General Aspects, Standardization, and Recommendations
257
Mikaelsson, Marianne; Oswaldsson, Ulla: Assaying the Circulating Factor VIII Activity in Hemophilia A Patients Treated with Recombinant Factor VIII Products
265
Saint-Remy, Jean-Marie R.: Immunology of Factor VIII Inhibitors
269
Brinkhous, Kenneth; Sandberg, Helena; Widlund, Lars; Read, Marjorie; Nichols, Timothy; Sigman, Jeffery; Oswaldsson, Ulla; Schaub, Robert G.; Mikaelsson, Marianne: Preclinical Pharmacology of Albumin-Free B-Domain Deleted Recombinant Factor VIII
273
Lusher, Jeanne M.: First and Second Generation Recombinant Factor VIII Concentrates in Previously Untreated Patients: Recovery, Safety, Efficacy, and Inhibitor Development
277
Suiter, Tobias M.: First and Next Generation Native rFVIII in the Treatment of Hemophilia A. What Has Been Achieved? Can Patients be Switched Safely?
285
Kreuz, Wolfhart; Ettingshausen, Carmen Escuriola; Zyschka, Alex; Oldenburg, Johannes; Saguer, Inmaculada Martinez; Ehrenforth, Silke; Klingebiel, Thomas: Inhibitor Development in Previously Untreated Patients with Hemophilia A: A Prospective Long-Term Follow-Up Comparing Plasma-Derived and Recombinant Products
291
Scandella, Dorothea: New Characteristics of Anti-Factor VIII Inhibitor Antibody Epitopes and Unusual Immune Responses to Factor VIII
297
Wikén, Margareta; Sjöberg, Katarina: Analysis of Samples from Patients Treated with ReFacto® for the Presence of Anti-SQ-Peptide Specific Antibodies
309
Klinge, Jens; Ananyeva, Natalya M.; Hauser, Charlotte A. E.; Saenko, Evgueni L.: Hemophilia A-From Basic Science to Clinical Practice

PREFACE

239
Mammen, Eberhard F.: Recombinant Factor VIII Products and Hemophilia A: Efficacy, Safety, and Inhibitor Development