DOI:
        10.1055/s-00000011
      
      
        DMW - Deutsche Medizinische Wochenschrift
      
      
        
          
            Issue S 2 ·
           Volume 130 ·
           July 2005
            
          
           DOI: 10.1055/s-002-4198 
          
            
          
          
          
  
    
      
    
  
  
        
        
  
  
  
  
    
  
  
  
    
  
  
  
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
    
      
    
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
  
        
          
            
              
              
              
                
                  
                    
                    
                      
                          
                          
                            
                            Editorial
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                            
                          
                          
                          
                          
  
    
      
        S61
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Middeke, M.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Evidence-based medicine and real-world studies using diabetes mellitus as paradigm
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                            
                            Übersichten
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                            
                          
                          
                          
                          
  
    
      
        S64
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Hauner, H.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Epidemiology and costs of diabetes mellitus in Germany
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S66
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Häussler, B.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Definition, procedure and targets of evidence-based medicine
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S72
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Perleth, M.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Expectations of cost bearer of clinical studies and transformation to care by physicians under contract
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S77
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Freemantle, N.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Real-world studies addressing real-world issues
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S82
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Rangoonwala, B.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Experiences with the realisation of innovative study designs taking the example of the HOPE-study
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S86
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Martin, S.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Retrolective study design - a new tool of evidence-based medicine
      
    
    
    
    
    
    
    
      
    
   
                      
                          
                          
                          
                          
                          
                            
                          
                          
                            
                          
                          
                          
                          
                          
                          
  
    
      
        S91
      
    
  
  
  
    
    
    
      
    
    
      
        
          
            
              
            
          
          
          
            
              
              Göke, B.: 
              
            
          
      
    
    
    
    
      
      
        
      
      
        
        
        
      
    
    
      
         Inhalative insulin in the real world