Thrombosis and Haemostasis

Issue 02 · August 2014

Review Article
189
Dickneite, Gerhard; Hoffman, Maureane:
Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

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Blood Coagulation, Fibrinolysis and Cellular Haemostasis
199
Hull, Russell D.; Liang, Jane; Bergqvist, David; Yusen, Roger D.:
Benefit-to-harm ratio of thromboprophylaxis for patients undergoing major orthopaedic surgery

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Supplementary Material

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213
Eriksson, Bengt I.; Agnelli, Giancarlo; Gallus, Alexander S.; Lassen, Michael R.; Prins, Martin H.; Renfurm, Ronny W.; Kashiwa, Makoto; Turpie, Alexander G. G.:
Darexaban (YM150) versus enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a randomised phase IIb dose confirmation study (ONYX-3)

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Supplementary Material

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226
Ammollo, Concetta T.; Semeraro, Fabrizio; Colucci, Mario; Simioni, Paolo:
Factor IX-Padua enhances the fibrinolytic resistance of plasma clots

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233
Majeed, Ammar; Meijer, Karina; Larrazabal, Ramiro; Arnberg, Fabian; Luijckx, Gert J.; Roberts, Robin S.; Schulman, Sam:
Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate

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240
Gouin-Thibault, Isabelle; Flaujac, Claire; Delavenne, Xavier; Quenet, Sara; Horellou, Marie-Hélenè; Laporte, Silvy; Siguret, Virginie; Lecompte, Thomas:
Assessment of apixaban plasma levels by laboratory tests: suitability of three anti-Xa assays

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249
Luxembourg, Beate; Pavlova, Anna; Geisen, Christof; Spannagl, Michael; Bergmann, Frauke; Krause, Manuela; Alesci, Sonja; Seifried, Erhard; Lindhoff-Last, Edelgard:
Impact of the type of SERPINC1 mutation and subtype of antithrombin deficiency on the thrombotic phenotype in hereditary antithrombin deficiency

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Platelets and Blood Cells
258
Darlington, Andrew; Tello-Montoliu, Antonio; Rollini, Fabiana; Ueno, Masafumi; Ferreiro, José Luis; Patel, Ronakkumar; Desai, Bhaloo; Guzman, Luis A.; Bass, Theodore A.; Angiolillo, Dominick:
Pharmacodynamic effects of standard dose prasugrel versus high dose clopidogrel in non-diabetic obese patients with coronary artery disease

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266
Olivier, Christoph B.; Diehl, Philipp; Schnabel, Katharina; Weik, Patrick; Zhou, Qian; Bode, Christoph; Moser, Martin:
Third generation P2Y₁₂ antagonists inhibit platelet aggregation more effectively than clopidogrel in a myocardial infarction registry

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Supplementary Material

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273
Laine, Marc; Frere, Corinne; Toesca, Richard; Berbis, Julie; Barnay, Pierre; Pansieri, Michel; Michelet, Pierre; Bessereau, Jacques; Camilleri, Elise; Ronsin, Olivia; Helal, Olfa; Paganelli, Franck; Dignat-George, Françoise; Bonello, Laurent:
Ticagrelor versus prasugrel in diabetic patients with an acute coronary syndrome

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279
Lei, Xi; Reheman, Adili; Hou, Yan; Zhou, Hui; Wang, Yiming; Marshall, Alexandra H.; Liang, Chaofan; Dai, Xiangrong; Li, Benjamin Xiaoyi; Vanhoorelbeke, Karen; Ni, Heyu:
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis

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Supplementary Material

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290
Straub, Niels; Beivers, Andreas; Lenk, Ekaterina; Aradi, Daniel; Sibbing, Dirk:
A model-based analysis of the clinical and economic impact of personalising P2Y₁₂-receptor inhibition with platelet function testing in acute coronary syndrome patients

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Cardiovascular Biology and Cell Signalling
300
Arbel, Yaron; Weitzman, Dahlia; Raz, Raanan; Steinvil, Arie; Zeltser, David; Berliner, Shlomo; Chodick, Gabriel; Shalev, Varda:
Red blood cell distribution width and the risk of cardiovascular morbidity and all-cause mortality

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308
Nencioni, Alessio; da Silva, Rafaela F.; Fraga-Silva, Rodrigo A.; Steffens, Sabine; Fabre, Mathias; Bauer, Inga; Caffa, Irene; Magnone, Mirko; Sociali, Giovanna; Quercioli, Alessandra; Pelli, Graziano; Lenglet, Sébastien; Galan, Katia; Burger, Fabienne; Calvo, Sara Vázquez; Bertolotto, Maria; Bruzzone, Santina; Ballestrero, Alberto; Patrone, Franco; Dallegri, Franco; Santos, Robson A. S.; Stergiopulos, Nikolaos; Mach, François; Vuilleumier, Nicolas; Montecucco, Fabrizio:
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

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Supplementary Material

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323
Bajar, Tarek M.; Winnicki, Wolfgang; Gensberger, Eva-Theres; Scharrer, Susanna I.; Regele, Heinz; Aumayr, Klaus; Kopecky, Chantal; Gmeiner, Bernhard M.; Hermann, Marcela; Zeillinger, Robert; Sengölge, Gürkan:
Known players, new interplay in atherogenesis: Chronic shear stress and carbamylated-LDL induce and modulate expression of atherogenic LR11 in human coronary artery endothelium

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Supplementary Material

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Cellular Proteolysis and Oncology
333
Xu, Na; Zhang, Yuan-Yuan; Lin, Yan; Bao, Bin; Zheng, Lei; Shi, Guo-Ping; Liu, Jian:
Increased levels of lysosomal cysteinyl cathepsins in human varicose veins: A histology study

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Supplementary Material

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Animal Models
345
Kager, Liesbeth M.; de Vos, Alex F.; Roelofs, Joris J. T. H.; van der Loos, Chris M.; de Boer, Onno J.; van’t Veer, Cornelis; Conway, Edward M.; Poll, Tom van der:
The thrombomodulin lectin-like domain does not change host responses to tuberculosis

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New Technologies, Diagnostic Tools and Drugs
354
Sciascia, Savino; Sanna, Giovanni; Murru, Veronica; Roccatello, Dario; Khamashta, Munther A.; Bertolaccini, Maria Laura:
Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome

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Supplementary Material

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365
Lukasz, Alexander; Beneke, Jan; Menne, Jan; Vetter, Frank; Schmidt, Bernhard M. W.; Schiffer, Mario; Haller, Hermann; Kümpers, Philipp; Kielstein, Jan T.:
Serum neutrophil gelatinase-associated lipocalin (NGAL) in patients with Shiga toxin mediated haemolytic uraemic syndrome (STEC-HUS)

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Letters to the Editor
373
Bundhoo, Shantu; Sagan, Ewelina; James, Philip E.; Anderson, Richard A.:
Clopidogrel results in favourable changes in nitric oxide metabolism in patients undergoing percutaneous coronary intervention

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Supplementary Material

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375
Rohla, Miklos; Freynhofer, Matthias K.; Hammerl, Herbert; Weiss, Thomas W.; Huber, Kurt:
Stroke and recurrent left atrial appendage thrombus in a patient with atrial fibrillation under old and new oral anticoagulants: A case report

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378
Musetti, Claudio; Quaglia, Marco; Cena, Tiziana; Rizzo, Antonietta; Stratta, Piero; Albano, Emanuele:
Anti-oxidised-phospholipid antibodies do not correlate with specific anti-phospholipid syndrome classes, but with disease duration

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Thrombosis and Haemostasis

Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

Benefit-to-harm ratio of thromboprophylaxis for patients undergoing major orthopaedic surgery

Darexaban (YM150) versus enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a randomised phase IIb dose confirmation study (ONYX-3)

Factor IX-Padua enhances the fibrinolytic resistance of plasma clots

Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate

Assessment of apixaban plasma levels by laboratory tests: suitability of three anti-Xa assays

Impact of the type of SERPINC1 mutation and subtype of antithrombin deficiency on the thrombotic phenotype in hereditary antithrombin deficiency

Pharmacodynamic effects of standard dose prasugrel versus high dose clopidogrel in non-diabetic obese patients with coronary artery disease

Third generation P2Y₁₂ antagonists inhibit platelet aggregation more effectively than clopidogrel in a myocardial infarction registry

Ticagrelor versus prasugrel in diabetic patients with an acute coronary syndrome

Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis

A model-based analysis of the clinical and economic impact of personalising P2Y₁₂-receptor inhibition with platelet function testing in acute coronary syndrome patients

Red blood cell distribution width and the risk of cardiovascular morbidity and all-cause mortality

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

Known players, new interplay in atherogenesis: Chronic shear stress and carbamylated-LDL induce and modulate expression of atherogenic LR11 in human coronary artery endothelium

Increased levels of lysosomal cysteinyl cathepsins in human varicose veins: A histology study

The thrombomodulin lectin-like domain does not change host responses to tuberculosis

Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome

Serum neutrophil gelatinase-associated lipocalin (NGAL) in patients with Shiga toxin mediated haemolytic uraemic syndrome (STEC-HUS)

Clopidogrel results in favourable changes in nitric oxide metabolism in patients undergoing percutaneous coronary intervention

Stroke and recurrent left atrial appendage thrombus in a patient with atrial fibrillation under old and new oral anticoagulants: A case report

Anti-oxidised-phospholipid antibodies do not correlate with specific anti-phospholipid syndrome classes, but with disease duration