DOI: 10.1055/s-00000075

Seminars in Respiratory and Critical Care Medicine

Issue 04 · Volume 40 · August 2019 DOI: 10.1055/s-009-44476 Serious Infections in the ICU: Evolving Concepts in Management and Prevention Guest Editors: Jean Chastre, MD, Charles-Edouard Luyt, MD, PhD, and Michel Wolff, MD

Preface

417
Chastre, Jean; Luyt, Charles-Edouard; Wolff, Michel: Serious Infections in the ICU: Evolving Concepts in Management and Prevention

Review Article

419
Strich, Jeffrey R.; Kadri, Sameer S.: Difficult-to-Treat Antibiotic-Resistant Gram-Negative Pathogens in the Intensive Care Unit: Epidemiology, Outcomes, and Treatment
435
Fierens, Jan; Depuydt, Pieter O.; De Waele, Jan J.: A Practical Approach to Clinical Antibiotic Stewardship in the ICU Patient with Severe Infection
447
Guery, Benoit; Calandra, Thierry: Early Antimicrobial Therapy for Sepsis: Does Each Hour Really Count?
454
Guillamet, M. Cristina Vazquez; Burnham, Jason P.; Kollef, Marin H.: Novel Approaches to Hasten Detection of Pathogens and Antimicrobial Resistance in the Intensive Care Unit
465
Heilmann, Eva; Gregoriano, Claudia; Schuetz, Philipp: Biomarkers of Infection: Are They Useful in the ICU?
476
Williams, Paul; Cotta, Menino Osbert; Roberts, Jason A.: Pharmacokinetics/Pharmacodynamics of β-Lactams and Therapeutic Drug Monitoring: From Theory to Practical Issues in the Intensive Care Unit
488
Cantan, Ben; Luyt, Charles-Edouard; Martin-Loeches, Ignacio: Influenza Infections and Emergent Viral Infections in Intensive Care Unit
498
Van de Louw, Andry; Mirouse, Adrien; Peyrony, Olivier; Lemiale, Virginie; Azoulay, Elie: Bacterial Pneumonias in Immunocompromised Patients
508
Buetti, Niccolò; Timsit, Jean-François: Management and Prevention of Central Venous Catheter-Related Infections in the ICU
524
Bassetti, Matteo; Giacobbe, Daniele R.; Vena, Antonio; Wolff, Michel: Diagnosis and Treatment of Candidemia in the Intensive Care Unit
540
Tudesq, Jean-Jacques; Peyrony, Olivier; Lemiale, Virginie; Azoulay, Elie: Invasive Pulmonary Aspergillosis in Nonimmunocompromised Hosts
548
Klompas, Michael: Prevention of Intensive Care Unit-Acquired Pneumonia
558
Kernéis, Solen; Lucet, Jean-Christophe: Controlling the Diffusion of Multidrug-Resistant Organisms in Intensive Care Units