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Angewandte Nuklearmedizin 2025; 48(04): 248-256
DOI: 10.1055/a-2414-3016
Nuklearkardiologie
Übersicht

Evidenzbasierte Einsatzmöglichkeiten der FDG-PET in der kardialen Entzündungsdiagnostik

Evidence-based applications of FDG-PET in cardiac inflammation diagnostics

Authors

  • Christian Uprimny

    1   Abteilung für Nuklearmedizin und Endokrinologie, Klinikum Klagenfurt am Wörthersee, Klagenfurt, Österreich

  • Stefan Sorko

    1   Abteilung für Nuklearmedizin und Endokrinologie, Klinikum Klagenfurt am Wörthersee, Klagenfurt, Österreich

  • Manfred Sorschag

    1   Abteilung für Nuklearmedizin und Endokrinologie, Klinikum Klagenfurt am Wörthersee, Klagenfurt, Österreich
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Zusammenfassung

Die FDG-PET ist eine etablierte Bildgebungsmethode in der Entzündungsdiagnostik und hat in den letzten Jahren bei bestimmten Indikationen in der Abklärung bzw. Diagnostik kardialer Entzündungen auch Einzug in die Leitlinien kardiologischer Fachgesellschaften gefunden. Konkret wird die FDG-PET in der Diagnostik der kardialen Sarkoidose sowie in der Endokarditisabklärung bei künstlichen Herzklappen und bei kardialen elektronischen Implantaten empfohlen. Der vorliegende Artikel soll einen klinisch orientierten Leitfaden zum Einsatz der FDG-PET bei diesen Fragestellungen bieten. Zudem werden für die kardiale Entzündungsdiagnostik notwendige Patient*innen-Vorbereitungsprotokolle diskutiert, die zur Reduktion der physiologischerweise bestehenden myokardialen FDG-Anreicherung führen und die Spezifität der myokardialen Entzündungs-FDG-PET erhöhen.

Abstract

FDG-PET is an established imaging technique in the diagnostic work-up of inflammatory diseases and has also found its place in current guidelines of cardiologic societies for certain indications regarding cardiac inflammation. In particular FDG-PET is recommended in the diagnosis of cardiac sarcoidosis and of infections in patients with prosthetic heart valves and cardiac implantable electronic devices. This article provides a guidance in these clinical questions. In addition patient preparation methods are discussed that lead to a reduction of the physiologically FDG-uptake of the heart, thus increasing specificity of cardiac inflammation FDG-PET.

Schlüsselwörter

FDG-PET - kardiale Entzündungsdiagnostik - kardiale Sarkoidose - Vorbereitungsprotokolle - Endokarditis

Keywords

FDG-PET - cardiac inflammation diagnostics - cardiac sarcoidosis - preparation protocols - endocarditis


Publication History

Article published online:
08 December 2025

© 2025. Thieme. All rights reserved.

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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